The impact of nut consumption on vascular endothelial function: a GRADE-assessed systematic review and meta-analysis of data from randomised controlled trials
Arabi SM, Rahnama I, Malek-Ahmadi M, Chambari M, Bahrami LS, Milkarizi N, Hatami A, Sukhorukov VN, Sahebkar A
International journal of food sciences and nutrition · 1 cita
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Russian Science Foundation
- Subvenciones
- Russian Science Foundation (24-45-20004)
Según 1 financiador declarado.
Publicación
- Publicado
- 2025-05-06 · Int J Food Sci Nutr · vol. 76 · número 4 · págs. 381–393
- Editorial
- Taylor & Francis
- Citado
- 0 citas · más que el 4% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 57 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Antioxidant Activity and Oxidative Stress · Meat and Animal Product Quality
- Palabras clave
- Meta-analysis, Nut, Medicine, Randomized controlled trial, Consumption (sociology), Internal medicine
- MeSH
- endothelium, vascular, humans, nuts, diet, vasodilation, adult, randomized controlled trials as topic, pulse wave analysis
9 autores
- Seyyed Mostafa Arabi🇮🇷University of Neyshabur; Neyshabur University of Medical Sciences
- Iman Rahnama
- Mahsa Malekahmadi🇮🇷Imam Khomeini Hospital; Tehran University of Medical Sciences
- Mahla Chambari🇲🇾UCSI University
- Leila Sadat Bahrami🇮🇷University of Neyshabur; Neyshabur University of Medical Sciences
- Narges Milkarizi🇮🇷Mashhad University of Medical Sciences
- Alireza Hatami🇮🇷Mashhad University of Medical Sciences
- Vasily N. Sukhorukov🇷🇺Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences
- Amirhossein Sahebkar🇮🇷🇨🇦🇮🇳 · autor de correspondenciaMashhad University of Medical Sciences; Biotechnology Research Center; Impact; Chitkara University
Resumen
El texto original del estudio, en el idioma en que se publicó.
This meta-analysis aimed to evaluate the effect of nut consumption on vascular endothelial function through the conduction of a comprehensive review of randomised controlled trials. We explored the major electronic databases for published RCTs examining the repercussions of nuts consumption on vascular endothelial function indicators in adults (>18 years). We used random-effects models to compute pooled estimates of weighted mean differences and confidence intervals. The protocol of the present study was registered in the international database of systematic review protocols (CRD42023472892). Nineteen articles, comprising 21 arms, were deemed eligible. According to the pooled estimations, eating nuts significantly improved flow-mediated dilation (FMD) (weighted mean difference (WMD): 1.12%, 95% CI 0.28 to 1.97, p p = 0.04). However, findings revealed that consuming nuts had no significant impact on pulse wave velocity (PWV), the index of augmentation (AIx), or heart rate. The endothelial function was considerably enhanced by nut consumption through the improvement of FMD, while the certainty of such evidence was assessed as very low.
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