Effect of repeated Low-Level red light therapy on axial length in myopic individuals: predictors for a good response
Kang D, Yuan L, Feng J, Yu R, Grzybowski A, Jin K, Sun W
BMC ophthalmology · 8 citas
Cómo se estudió
- Diseño
- Estudio de cohortes (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- Natural Science Foundation of China
- Subvenciones
- National Natural Science Foundation of China (82201195); National Natural Science Foundation of China (82201197)
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-05-07 · BMC Ophthalmol · vol. 25 · número 1 · pág. 273
- Editorial
- BioMed Central
- Citado
- 8 citas · más que el 96% de estudios similares · 4.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 38 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Ophthalmology and Visual Impairment Studies · Corneal surgery and disorders · Ocular Surface and Contact Lens
- Palabras clave
- Medicine, Ophthalmology
- MeSH
- humans, myopia, refraction, ocular, treatment outcome, intraocular pressure, visual acuity, adult, middle aged, female, male, young adult, axial length, eye, low-level light therapy
7 autores
- Daohuan Kang🇨🇳Children's Hospital of Zhejiang University
- Lu Yuan🇨🇳Children's Hospital of Zhejiang University
- Jia Hui Feng🇨🇳Children's Hospital of Zhejiang University
- Rui Yu🇨🇳Children's Hospital of Zhejiang University
- Andrzej E. Grzybowski
- Kai Pu Jin🇨🇳 · autor de correspondenciaSecond Affiliated Hospital of Zhejiang University
- Wen Jie Sun🇨🇳 · autor de correspondenciaChildren's Hospital of Zhejiang University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
This study aimed to investigate the effects of Repeated Low-Level Red Light (RLRL) therapy on axial length (AL) in myopic individuals and to identify key predictors for a good response to the treatment, with a focus on baseline ocular characteristics and treatment compliance.
Methods
A total of 91 participants were enrolled, with 50 classified in the poor responders' group and 41 in the good responders' group. Baseline characteristics, including age, gender, pupil constriction diameter (PCD), intraocular pressure (IOP), spherical equivalent refraction (SER), AL, corneal curvature (ACC), and choroidal thickness (CT) were recorded. Compliance and AL changes were tracked over one year. Univariable and multivariable analyses identified factors associated with AL changes.
Results
Good responders' group showed a significant AL reduction (-0.29 ± 0.16 mm, p < 0.001), while poor responders' group had an increase (+ 0.23 ± 0.12 mm, p < 0.001). Good responders' group had lower initial SER (-4.15 ± 2.87 D vs. -2.62 ± 1.80 D, p = 0.004) and longer AL (24.76 ± 1.21 mm vs. 24.15 ± 0.99 mm, p = 0.010). Both groups showed CT changes (p < 0.001), with greater increases in good responders. Univariable analysis identified initial AL and SER as predictors of a good response (both p < 0.001). Compliance showed a trend toward significance in multivariable analysis (β = -0.196, p = 0.052).
Conclusion
Longer baseline AL and lower SER are key predictors of a good response to RLRL therapy. Moreover, treatment compliance showed a trend toward significance, emphasizing its crucial role in achieving optimal outcomes.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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