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Efficacy of repeated low-level red-light therapy combined with defocus incorporated multiple segments spectacles for controlling childhood myopia

Luo CK, Lai CY, Tan JH, Zhao W, Tan QQ

Photodiagnosis and photodynamic therapy · 4 citas

Cómo se estudió

Diseño
Ensayo clínico controlado (clasificado por nuestro filtro de IA)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Universidad u hospital
North Sichuan Medical College

Según 1 financiador declarado.

Publicación

Publicado
2025-06-13 · Photodiagnosis Photodyn Ther · vol. 54 · pág. 104681
Editorial
Elsevier BV
Citado
5 citas · más que el 92% de estudios similares · 3.1× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
34 trabajos
Acceso
Acceso abierto (revista) · CC-BY-NC-ND
Áreas de investigación
Ophthalmology and Visual Impairment Studies · Corneal surgery and disorders · Retinopathy of Prematurity Studies
Palabras clave
Medicine, Optometry, Ophthalmology
MeSH
humans, myopia, refraction, ocular, treatment outcome, eyeglasses, adolescent, child, female, male, low-level light therapy

5 autores

  • Chang-Kang Luo🇨🇳North Sichuan Medical University; Affiliated Hospital of North Sichuan Medical College
  • Chun-Yan Lai🇨🇳North Sichuan Medical University; Affiliated Hospital of North Sichuan Medical College
  • Jia-Hao Tan🇨🇳 · autor de correspondenciaNorth Sichuan Medical University; Affiliated Hospital of North Sichuan Medical College
  • Wei Zhao🇨🇳North Sichuan Medical University; Affiliated Hospital of North Sichuan Medical College
  • Qing‐Qing Tan🇨🇳 · autor de correspondenciaNorth Sichuan Medical University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objective

To evaluate the differences in the efficacy of repeated low-level red-light (RLRL) therapy combined with either single-vision spectacles (SVS) or defocus incorporated multiple segments (DIMS) spectacles in slowing myopia progression in children.

Methods

A total of 129 myopic children aged 6-14 years were recruited between July 2023 and February 2024. Participants had at least one eye with spherical equivalent refraction (SER) <-0.50D and astigmatism ≤ 3.00D after cycloplegia. They were divided into four groups: SVS, DIMS, RLRL combined with SVS (RCS), and RLRL combined with DIMS (RCD). The RCS and RCD groups wore spectacles and received daily RLRL therapy sessions. The primary outcome was the change in axial length (AL) at 12 months.

Results

After 12 months, the mean changes of AL were: 0.26 mm (95 % CI, 0.17 to 0.35 mm) for SVS, 0.16 mm (95 % CI, 0.11 to 0.21 mm) for DIMS, -0.21 mm (95 % CI, -0.45 to 0.02 mm) for RCS, and -0.14 mm (95 % CI, -0.27 to -0.01 mm) for RCD. Significant differences were observed between groups (F = 15.18, P 0.05). No severe adverse events or safety concerns related to RLRL therapy were observed throughout the study.

Conclusion

RLRL therapy is a potentially effective and practical approach for myopia control, demonstrating comparable efficacy when combined with either SVS or DIMS spectacles.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).

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