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L-type association between magnesium intake and human papillomavirus infection in US adult women: based on NHANES 2003-2016 data

Chen H, Chen X, Chen Y, Tang L, Shi WJ, Ou YH

Frontiers in nutrition · 0 citas

Cómo se estudió

Diseño
Estudio transversal (clasificado por nuestro filtro de IA)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Natural Science Foundation of China
Gobierno
Centers for Disease Control and Prevention
Gobierno
Basic and Applied Basic Research Foundation of Guangdong Province
Subvenciones
National Natural Science Foundation of China (82201871)

Según 3 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2025-05-30 · Front Nutr · vol. 12 · pág. 1594489
Editorial
Frontiers Media
Citado
1 cita · más que el 62% de estudios similares · 0.5× el promedio de su campo
Referencias
70 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Magnesium in Health and Disease · Preterm Birth and Chorioamnionitis · Bone health and osteoporosis research
Palabras clave
National Health and Nutrition Examination Survey, Human papillomavirus, Medicine, Association (psychology), Internal medicine, Physiology, Environmental health, Population, Psychology

6 autores

  • Haiwei Chen🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
  • Xiaotong Chen🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
  • Yuling Chen🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
  • Lixin Tang🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
  • Wenjing Shi🇨🇳 · autor de correspondenciaSecond Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
  • Yong-jun Ou🇨🇳 · autor de correspondenciaSecond Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

In the post-vaccine era, adjusting living habits and diet structure has become a new way to prevent Human papillomavirus(HPV). Although dietary factors have received much attention, the association of dietary magnesium with HPV infection remains understudied.

Method

Using NHANES cross-sectional data from 2003 to 2016, this study analyzed the relationship between magnesium intake and HPV infection in 7,246 women aged 18-59 years. Weighted logistic regression and subgroup analysis assessed independent links, while curve fitting and threshold analysis defined dose response and saturation.

Result

A significant negative correlation was observed between magnesium intake and the risk of HPV infection. After comprehensive adjustment for potential confounding factors, individuals in the highest quartile of magnesium intake exhibited a statistically significant 29.7% reduction in the risk of HPV infection for each additional unit, compared to those in the lowest quartile (CI:0.554-0.894, p = 0.005). Besides, using smooth curve fitting and threshold analysis, we found an L-shaped dose response between magnesium intake and HPV risk. Below 401 mg/day of magnesium, increased intake is inversely correlated with HPV infection risk. Above this threshold, further increases plateaued in risk reduction.

Conclusion

Moderate magnesium intake has a protective effect against HPV infection. Rationally increasing magnesium intake through dietary channels is expected to serve as an effective preventive measure against HPV infection.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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