Additional Effect of Exercise to Intermittent Fasting on Body Composition and Cardiometabolic Health in Adults With Overweight/obesity: A Systematic Review and Meta-analysis
Dai ZH, Wan KW, Wong PS, Huang WY, Yu AP, Wong SH
Current obesity reports · 8 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-06-19 · Curr Obes Rep · vol. 14 · número 1 · pág. 54
- Editorial
- Springer Science+Business Media
- Citado
- 10 citas · más que el 85% de estudios similares · 1.9× el promedio de su campo
- Referencias
- 70 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Cardiovascular and exercise physiology · Physical Activity and Health
- Palabras clave
- intermittent fasting, physical activity, overweight, obesity, body composition, cardiometabolic health, fat mass, waist circumference, insulin resistance, glycemic control, LDL cholesterol, resting heart rate, cardiorespiratory fitness, VO2max, combined diet and exercise intervention, weight loss, HbA1c, HOMA-IR, triglycerides, HDL cholesterol, blood pressure
- MeSH
- humans, obesity, exercise, exercise therapy, fasting, body composition, adult, middle aged, female, male, overweight, intermittent fasting
6 autores
- Zi-han Dai🇭🇰Chinese University of Hong Kong
- Kewen Wan🇭🇰Hong Kong Baptist University
- Po-san Wong🇭🇰Chinese University of Hong Kong
- Yajun Huang🇭🇰Hong Kong Baptist University
- Angus P. Yu🇭🇰Chinese University of Hong Kong
- Stephen Heung‐Sang Wong🇭🇰 · autor de correspondenciaChinese University of Hong Kong
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
The purpose of this study is to evaluate the additional effect of exercise to intermittent fasting (IF) on body composition and cardiometabolic health in adults with overweight/obesity.
Method
Relevant studies were identified through a systematic search across five databases. A random-effects meta-analysis was conducted on outcomes including body composition and cardiometabolic health markers, to compare the effect of combining IF with exercise against IF alone. The certainty of the evidence was evaluated using the GRADE approach, while the quality of the included studies was assessed using the revised Cochrane risk-of-bias tool and the TESTEX scale.
Result
In total, twelve studies including 616 participants (Age: 40 ± 9 years; BMI: 33.6 ± 4.8 kg/m2; 87.3% female) were included in this systematic review and meta-analysis. The combined intervention was more effective, leading to greater reductions in fat mass (-0.93 kg [95% CI: -1.69, -0.18]) and waist circumference (-2.51 cm [95% CI: -3.70, -1.32]) when compared to IF alone. Cardiometabolic health parameters also showed greater improvements, with decreased insulin (-3.1uIU/ml [95%CI: -4.25; -1.95]), HOMA-IR (-0.57 [95%CI: -0.83; -0.31]), LDL (-10.67 mg/dl [95%CI: -20; -1.35]), resting heart rate (-2.68 bpm [95%CI: -4.71; -0.64]), along with enhanced cardiorespiratory fitness (VO2 max:1.92 ml/kg/min [95%CI: 0.32; 3.52]). For the remaining outcome variables, no statistically meaningful differences emerged between the groups.
Conclusion
The potential benefits of incorporating exercise into IF for adults with overweight/obesity, particularly in terms of body composition, glycemic control, and cardiorespiratory fitness, appear promising. Nevertheless, given the limited amount of data, future investigations are essential to strengthen the evidence base and investigate the influence of specific exercise and IF types in enhancing treatment outcomes. Registry and registry number for systematic reviews or meta-analyses: CRD42024550753.
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