Benefits of Short-Term (4-Week) Daily Walnut Consumption in Middle-Aged Adults at Risk for Metabolic Syndrome: Outcomes of a Randomized Controlled Trial
Mateș L, Albert-Ani D, Fizeșan I, Petru AE, Banc R, Rusu ME, Costache C, Filip L, Popa DS, Leucuța DC
Nutrients · 2 citas
Etiquetas de revisión
Alimentación controladaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Comida provista por los investigadores
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Universitatea de Medicină şi Farmacie Iuliu Haţieganu Cluj-Napoca
- Universidad u hospital
- Iuliu Hațieganu University of Medicine and Pharmacy
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-06-21 · Nutrients · vol. 17 · número 13 · pág. 2072
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 6 citas · más que el 92% de estudios similares · 3.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 65 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Nutrition, Genetics, and Disease
- Palabras clave
- walnut consumption, Juglans regia, metabolic syndrome, middle-aged adults, soluble VCAM-1, endothelial function, waist circumference, fasting blood glucose, lipid profile, dietary supplementation, cardiovascular risk
- MeSH
- humans, juglans, nuts, blood glucose, lipids, vascular cell adhesion molecule-1, diet, cross-over studies, adult, middle aged, female, male, metabolic syndrome
10 autores
- Letiția Mateș🇷🇴Iuliu Hațieganu University of Medicine and Pharmacy
- Doina Albert-Ani🇷🇴Spitalul Clinic Județean de Urgență Cluj-Napoca
- Ionel Fizeșan🇷🇴Iuliu Hațieganu University of Medicine and Pharmacy
- Andreea-Elena Petru🇷🇴Iuliu Hațieganu University of Medicine and Pharmacy
- Roxana Banc🇷🇴 · autor de correspondenciaIuliu Hațieganu University of Medicine and Pharmacy
- Marius Emil Rusu🇷🇴Iuliu Hațieganu University of Medicine and Pharmacy
- Carmen Anca Costache🇷🇴Iuliu Hațieganu University of Medicine and Pharmacy; Spitalul Clinic Județean de Urgență Cluj-Napoca
- Lorena A. Filip🇷🇴Iuliu Hațieganu University of Medicine and Pharmacy; Academia Oamenilor de Știință din România
- Daniela‐Saveta Popa🇷🇴Iuliu Hațieganu University of Medicine and Pharmacy
- Daniel‐Corneliu Leucuta🇷🇴Iuliu Hațieganu University of Medicine and Pharmacy
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background: Epidemiological research has shown that regular walnut (from Juglans regia L.) consumption is associated with a reduced risk of cardiovascular disease (CVD), potentially attributable to their antioxidant and anti-inflammatory properties. The vascular cellular adhesion molecule-1 (VCAM-1), a protein upregulated in CVD, has been previously examined in relation to walnut consumption. However, the clinical findings regarding the effects of walnuts on endothelial function among middle-aged individuals susceptible to metabolic syndrome (MetS) remain inconclusive. Objective: This study examined the effects of daily walnut consumption over a four-week period on cardiometabolic parameters (lipid and glycemic profiles, as well as soluble VCAM-1 levels) and anthropometric measurements in middle-aged individuals with at least one altered MetS parameter and no medication. Methods: In a randomized controlled cross-over trial, 22 eligible Caucasian participants (48.81 ± 4.3 years) were selected and randomly assigned to receive either 45 g of walnuts per day or no walnuts within a controlled diet. There were two 28-day intervention periods, with a one-month washout period in between. Clinical and biochemical evaluations were conducted at the beginning and end of each intervention period. Results: A total of 20 participants completed the intervention and were analyzed, with walnuts being well tolerated. A significant decrease in waist circumference (p = 0.049) and a slight change in fasting blood glucose (p = 0.089) were noted following walnut intake. Conclusions: Short-term (4 weeks) dietary supplementation with walnuts resulted in a statistically significant reduction in waist circumference while not impacting the overall health status of participants. Longer-term studies are necessary to investigate the benefits of daily walnut consumption and its impact on the onset and development of MetS in this age group.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.