The Associations of Dietary Copper and Magnesium Intake, Geriatric Nutritional Risk Index, and Systemic Inflammation Response Index with Stroke Risk in the Elderly
Luo B, Liu S, Zheng L, Zhang B, Zou W
Balkan medical journal · 3 citas
Cómo se estudió
- Diseño
- Estudio transversal (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Centers for Disease Control and Prevention
Según 1 financiador declarado.
Publicación
- Publicado
- 2025-08-19 · Balkan Med J · vol. 42 · número 5 · págs. 452–463
- Editorial
- Galenos Yayinevi
- Citado
- 2 citas · más que el 75% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 2 trabajos
- Acceso
- Acceso abierto (publicación gratuita) · CC-BY-NC-ND
- Áreas de investigación
- Magnesium in Health and Disease · Trace Elements in Health · Nutritional Studies and Diet
- Palabras clave
- Medicine, Stroke (engine), Systemic inflammation, Index (typography), Internal medicine, Inflammation, Body mass index, Gerontology
- MeSH
- humans, inflammation, magnesium, copper, diet, geriatric assessment, nutrition surveys, logistic models, risk assessment, risk factors, cross-sectional studies, nutritional status, aged, aged, 80 and over, female, male, stroke
5 autores
- Baochun Luo🇨🇳Heilongjiang University of Chinese Medicine
- Sifan Liu🇨🇳Heilongjiang University of Chinese Medicine
- Lei Zheng🇨🇳Heilongjiang University of Chinese Medicine; First Affiliated Hospital of Heilongjiang University of Chinese Medicine
- Baiwen Zhang🇨🇳Heilongjiang University of Chinese Medicine; First Affiliated Hospital of Heilongjiang University of Chinese Medicine
- Wei Zou🇨🇳Heilongjiang University of Chinese Medicine; First Affiliated Hospital of Heilongjiang University of Chinese Medicine
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The effects of dietary copper and magnesium intake, the geriatric nutritional risk index (GNRI), and the systemic inflammation response index (SIRI) on stroke risk in the elderly remain unclear.
Aims
To examine the relationships between dietary copper and magnesium intake, GNRI, SIRI, and stroke risk in the elderly.
Study design
Cross-sectional study.
Methods
Data from 7,157 elderly participants in National Health and Nutrition Examination Survey 2007-2016 were analyzed using multifactorial logistic regression, subgroup analysis, smooth curve fitting, threshold effect analysis, mediation analysis, and sensitivity analysis.
Results
Higher dietary copper and magnesium intake were significantly and linearly associated with lower stroke risk. SIRI was positively associated with stroke risk, while GNRI had a stable protective effect. In fully adjusted models, medium- and high-level copper and magnesium intake were positively associated with GNRI and negatively associated with SIRI. GNRI mediated 4.4% and 5.5% of the associations between copper and magnesium intake and stroke risk, respectively; SIRI mediated 3.4% and 2.9%, respectively.
Conclusion
Higher dietary copper and magnesium intake are associated with reduced stroke risk in the elderly, with GNRI and SIRI exerting modest mediating effects.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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