Consumption of Ultra-Processed Foods and Metabolic Parameters in Type 2 Diabetes Mellitus: A Cross-Sectional Study
Bauer J, Ayala FO, Marcadenti A, Machado RHV, Cristina Bersch-Ferreira Â, Moreira MFS, Beretta MV, Feoli AMP, Busnello FM
International journal of environmental research and public health · 3 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- PROADI SUS
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-08-14 · Int J Environ Res Public Health · vol. 22 · número 8 · pág. 1275
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 2 citas · más que el 84% de estudios similares · 1.7× el promedio de su campo
- Referencias
- 42 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Diet, Metabolism, and Disease
- Palabras clave
- ultra-processed foods, type 2 diabetes, NOVA classification, HbA1c, fasting blood glucose, lipid profile, LDL cholesterol, total cholesterol, body mass index, waist circumference, cardiovascular risk
- MeSH
- humans, diabetes mellitus, type 2, blood glucose, body mass index, diet, cross-sectional studies, food handling, adult, aged, middle aged, female, male, waist circumference, fast foods, glycated hemoglobin, food, processed
9 autores
- Júlia Bauer🇧🇷Universidade Federal de Ciências da Saúde de Porto Alegre
- Fernanda Oliveira Ayala🇧🇷Universidade Federal de Ciências da Saúde de Porto Alegre
- Aline Marcadenti
- Rachel Helena Vieira Machado
- Ângela Cristine Bersch-Ferreira
- Maria Fernanda Souza Moreira🇧🇷Universidade Federal de Ciências da Saúde de Porto Alegre
- Mileni Vanti Beretta🇧🇷Universidade Federal de Ciências da Saúde de Porto Alegre
- Ana Maria Pandolfo Feóli🇧🇷Pontifícia Universidade Católica do Rio Grande do Sul
- Fernanda Michielin Busnello🇧🇷 · autor de correspondenciaUniversidade Federal de Ciências da Saúde de Porto Alegre
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Understanding how food processing impacts type 2 diabetes (T2DM) control is essential for disease management. This study aimed to assess the association between ultra-processed food (UPF) consumption, as defined by the NOVA classification, and metabolic parameters in T2DM patients.
Methods
This was a cross-sectional analysis using baseline data from the NUGLIC study, a multicenter randomized clinical trial. Multiple linear and Poisson regressions were used to evaluate associations between quintiles of processed and ultra-processed food consumption and glycated hemoglobin (HbA1c) as the primary outcome. Secondary outcomes included fasting glucose, lipid profile, body mass index (BMI), and waist circumference.
Results
This study included 326 participants. UPF consumption accounted for approximately 16.4% of total daily energy intake. No significant linear associations were observed between higher consumption of industrialized foods and anthropometric or glycemic markers. However, intermediate and high consumption levels were associated with an increased total cholesterol (Q3: β = 26.6; Q4: β = 26.7) and LDL-cholesterol (Q4: β = 19.8; Q5: β = 17.5).
Conclusion
In T2DM patients, a higher intake of processed and ultra-processed foods was linked to elevated cholesterol and LDL levels. These findings highlight potential cardiovascular risks but do not support causality due to the study's cross-sectional design.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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