Effect of Time-Restricted Eating Versus Daily Calorie Restriction on Mood and Quality of Life in Adults with Type 2 Diabetes
Pavlou V, Lin S, Cienfuegos S, Ezpeleta M, Runchey MC, Corapi S, Varady KA
Nutrients · 1 cita
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Department of Kinesiology and Nutrition, University of Illinois Chicago
- Autores
- Al menos un autor declara un vínculo económico con la industria
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-08-26 · Nutrients · vol. 17 · número 17 · pág. 2757
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 2 citas · más que el 78% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 26 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Eating Disorders and Behaviors · Nutritional Studies and Diet
- Palabras clave
- time-restricted eating, caloric restriction, type 2 diabetes, mood, quality of life, depression, total mood disturbance, weight loss, fat mass, visceral fat, lean body mass
- MeSH
- humans, diabetes mellitus, type 2, weight loss, caloric restriction, fasting, depression, affect, time factors, quality of life, adult, aged, middle aged, female, male
7 autores
- Vasiliki Pavlou🇺🇸University of Illinois Chicago
- Shuhao Lin🇺🇸University of Illinois Chicago
- Sofia Cienfuegos🇺🇸University of Illinois Chicago
- Mark Ezpeleta🇺🇸University of Colorado Anschutz; University of Colorado Denver
- Mary-Claire Runchey🇺🇸University of Illinois Chicago
- Sarah Corapi🇺🇸University of Illinois Chicago
- Krista A Varady🇺🇸 · autor de correspondenciaUniversity of Illinois Chicago
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background/objectives
This secondary analysis aimed to compare the effects of time-restricted eating (TRE) versus calorie restriction (CR) and controls on mood and quality of life in adults with type 2 diabetes (T2D).
Methods
Adults with T2D (n = 69) were randomly assigned to one of three interventions for 6 months: 8 h TRE (eating only between 12 and 8 pm daily); CR (25% energy restriction daily); or a no-intervention control group. At baseline and 6 months, mood was assessed using the Beck Depression Inventory-II (BDI-II) and the Profile of Mood States (POMS) questionnaires, while quality of life was assessed using the Rand 36-Item Short Form (SF-36).
Results
Body weight significantly decreased in the TRE group (-3.38%; 95% CI, -6.04 to -0.71%, p = 0.008), but not in the CR group (-1.80%, 95% CI, -4.50 to 0.91%, p = 0.32) versus controls by month 6. Fat mass, lean mass, and visceral fat mass remained unchanged in TRE and CR groups, versus controls, from baseline to month 6. No changes were observed in depression scores (BDI-II), total mood disturbance, or any POMS subscales (tension, depression, anger, fatigue, confusion, or vigor) in either the TRE or CR groups compared to controls. Similarly, there were no significant changes in the quality-of-life SF-36 constructs of vitality, bodily pain, mental health, and general physical health in the TRE or CR group versus controls. By month 6, there were no associations between changes in body weight, quality of life, and mood outcomes in any group.
Conclusions
In conclusion, our findings suggest that TRE and CR do not have any effect on mood or quality of life in adults with T2D, relative to controls. However, the participants' baseline mood and quality of life were generally within healthy ranges, and only minimal weight loss was achieved (3.5%, TRE only), which may explain the lack of observed effects.
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