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Revisión sistemática2025Financiado por la industriaVínculos de autores con la industriaAcceso abierto

Financiado en parte por Australian Eggs, Australian Eggs Ltd

Egg intake and cognitive function in healthy adults: A systematic review of the literature

Sultan N, Kellow NJ, Tuck CJ, Cheng E, MacMahon C, Biesiekierski JR

The journal of nutrition, health & aging · 0 citas

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Vínculos de autores con la industriaFinanciado por la industria

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Cómo se estudió

Diseño
Revisión sistemática (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiado por la industria
Grupo de la industria
Australian Eggs
Gobierno
National Health and Medical Research Council
Grupo de la industria
Australian Eggs Ltd
Autores
Al menos un autor declara un vínculo económico con la industria
Subvenciones
National Health and Medical Research Council (2025943); Australian Eggs (GROW005)

Según 3 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2025-10-07 · J Nutr Health Aging · vol. 29 · número 12 · pág. 100696
Editorial
Springer Science+Business Media
Citado
4 citas · más que el 69% de estudios similares · 0.9× el promedio de su campo
Referencias
70 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Nutritional Studies and Diet · Fatty Acid Research and Health · Antioxidant Activity and Oxidative Stress
Palabras clave
Cognition, Dementia, Intervention (counseling), Consumption (sociology), Cognitive decline, Cognitive aging
MeSH
humans, diet, cognition, eggs, adult, aged, middle aged, female, male, cognitive dysfunction

6 autores

  • Nessmah Sultan🇦🇺Monash University
  • Nicole J. Kellow🇦🇺Monash University
  • Caroline J. Tuck🇦🇺Swinburne University of Technology
  • T.C.E. Cheng🇦🇺Monash University
  • Clare MacMahon🇦🇺La Trobe University
  • Jessica R. Biesiekierski · autor de correspondencia

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Cognitive decline is a growing public health concern, particularly in aging populations. Eggs are a widely consumed, nutrient-dense food containing choline, phospholipids, tryptophan, and omega-3 fatty acids, which individually support cognitive processes such as memory, attention, and neurogenesis. While these individual nutrients have demonstrated benefits in supplementation studies, the cognitive effects of whole egg consumption are not well established. This systematic review aimed to evaluate the association between whole egg consumption and cognitive function in healthy adults.

Methods

A systematic search of five electronic databases (Medline, Embase, CINAHL Plus, SCOPUS, and PsychInfo) was conducted from database inception through February 2025. Studies were included if they investigated whole egg intake in relation to cognitive outcomes in healthy adults. Risk of bias was assessed using tools appropriate to study design. Due to heterogeneity in study methods, outcomes were synthesised narratively. Cognitive outcomes were categorised into domains including global cognitive function, memory, executive function, language, processing speed, and dementia risk.

Results

Eleven studies met the inclusion criteria: one pre-post intervention study, six prospective cohort studies, three cross-sectional studies, and one case-control study. Study populations were predominantly older adults and included >38,000 participants. Two studies reported a reduced risk of dementia or cognitive impairment associated with moderate egg consumption (approximately 0.5-1 egg per day), while one study found increased risk at high intake levels (Over 1 egg per day). Several studies showed improvements in memory, verbal fluency, or processing speed with moderate-but not high-egg intake. The pre-post study reported improved reaction time following eight weeks of daily egg consumption (2 eggs per day). Heterogeneity in exposure measurement and cognitive testing methods limited direct comparisons across studies.

Discussion

Moderate whole egg consumption may be associated with improvements in cognitive outcomes in healthy adults, including reduced dementia risk and better memory performance. However, findings are inconsistent and limited by differences in study design, dietary assessment, and cognitive testing. Further well-controlled intervention studies are needed to determine optimal intake levels, explore mechanisms, and assess whether eggs can be integrated meaningfully into dietary strategies to support cognitive aging. (PROSPERO registration: 408532).

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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