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Metaanálisis2025Acceso abierto

The efficacy of music therapy for post-stroke depression: A meta-analysis

Li Y, Peng Y, Ma S

Medicine · 1 cita

Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente

Según la declaración de financiación del texto completo.

Publicación

Publicado
2025-10-24 · Medicine (Baltimore) · vol. 104 · número 43 · pág. e44949
Editorial
Wolters Kluwer
Citado
2 citas · más que el 60% de estudios similares · 0.5× el promedio de su campo
Referencias
7 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Music Therapy and Health · Stroke Rehabilitation and Recovery · Art Therapy and Mental Health
Palabras clave
music therapy, post-stroke depression, depressive symptoms, anxiety, activities of daily living, neurological deficit, serotonin, stroke rehabilitation, Hamilton Depression Rating Scale, Barthel Index
MeSH
humans, treatment outcome, music therapy, depression, randomized controlled trials as topic, stroke

3 autores

  • Yan Li🇨🇳Guilin University of Aerospace Technology
  • Yanmei Peng🇨🇳Guilin University of Aerospace Technology
  • Shiwen Ma🇨🇳 · autor de correspondenciaGuilin University of Aerospace Technology

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Music can stimulate the central nervous system and may exert calming, analgesic, and negative emotion-reducing effects. It has been applied in the treatment of various psychological disorders, including post-stroke depression (PSD). This study systematically assesses the efficacy of music therapy in improving depressive symptoms in patients with PSD.

Methods

A comprehensive search was conducted in 9 databases including Web of Science, PubMed, EMBASE, CNKI, VIP, and Wanfang, covering all publications up to January 7, 2024. Two researchers independently screened articles on music therapy interventions for PSD. Quality assessment and meta-analysis were performed using RevMan 5.3.

Results

A total of 37 randomized controlled trials with 2776 patients were included in the study. Meta-analysis showed that music was effective in improving Hamilton depression scale scores (mean differences [MD] = -4.76, 95% confidence interval [CI]: -6.11 to -3.40, P < .00001), Zung Self-Rating Depression Scale scores (MD = -5.25, 95% CI: -6.20 to -4.30, P < .00001), Zung Self-Rating Anxiety Scale scores (MD = -7.34, 95% CI: -8.71 to -5.97, P < .00001), Barthel index (MD = 13.59, 95% CI: 6.83-20.35, P < .00001, activities of daily living scores (MD = 13.09, 95% CI: 4.12-22.05, P < .00001), neurological deficit score (standardized mean difference = -1.62, 95% CI: -1.88 to -1.35, P < .00001), 5-hydroxytryptamine (MD = 0.86, 95% CI: 0.56-1.16, P < .00001) in PSD patients compared to the conventional rehabilitation group.

Conclusion

Music therapy has demonstrated significant clinical efficacy in improving depressive symptoms, daily living skills, the degree of neurological deficits, and serum 5-hydroxytryptamine levels in individuals with PSD.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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