The effectiveness of low-level laser therapy for chronic rhinosinusitis: A systematic review and meta-analysis
Park YS, Kim MS, Cho JH, Kang YJ
Lasers in medical science · 0 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2025-11-15 · Lasers Med Sci · vol. 40 · número 1 · pág. 478
- Editorial
- Springer Science+Business Media
- Citado
- 1 cita · más que el 46% de estudios similares · 0.2× el promedio de su campo
- Referencias
- 25 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Sinusitis and nasal conditions · Photodynamic Therapy Research Studies
- Palabras clave
- Randomized controlled trial, Cochrane Library, Low level laser therapy, Chronic rhinosinusitis, MEDLINE, Sample size determination, Meta-analysis, Web of science
- MeSH
- humans, sinusitis, rhinitis, chronic disease, treatment outcome, low-level light therapy, rhinosinusitis
4 autores
- Youn Sun Park🇰🇷The Catholic University of Korea Yeouido St. Mary's Hospital; Catholic University of Korea
- Min Su Kim🇰🇷The Catholic University of Korea Yeouido St. Mary's Hospital; Catholic University of Korea
- Jin‐Hee Cho🇰🇷The Catholic University of Korea Yeouido St. Mary's Hospital; Catholic University of Korea
- Yun Jin Kang🇰🇷 · autor de correspondenciaThe Catholic University of Korea Yeouido St. Mary's Hospital; Catholic University of Korea
Resumen
El texto original del estudio, en el idioma en que se publicó.
This systematic review and meta-analysis is aimed to assess the efficacy and the safety of low-level laser therapy (LLLT) and photobiomodulation (PBMT) in the management of chronic rhinosinusitis (CRS). A comprehensive search of PubMed, SCOPUS, Embase, Web of Science, and Cochrane Library databases were conducted for studies published up to June 30th, 2025. Eligible studies included patients with CRS who underwent LLLT or PBMT, and reported quantitative outcomes. Primary outcomes were subjective symptom scores, while secondary outcomes such as headache, fatigue, and computed tomography (CT) findings were analyzed when available. Six studies including 162 patients were analyzed. LLLT or PBMT was associated with significant improvement in subjective symptom scores at 2 weeks (SMD 0.64; 95% CI [0.26; 1.01], I² = 0%, p = 0.0009), at 4 weeks (SMD 2.66; 95% CI [1.14; 4.19], I² = 92%, p = 0.0006), and at 2-6 months (SMD 0.86; 95% CI [0.39; 1.33], I² = 0%, p = 0.0003). However, no significant improvement was observed in objective CT-based measures (SMD 0.34; 95% CI [-0.01; 0.69], I² = 0%, p = 0.06), and also secondary outcomes such as headache and fatigue showed no consistent benefit. The largest effect was observed at 4 weeks, but this result should be interpreted with caution given the extreme heterogeneity across studies. LLLT and PBMT appear to provide symptomatic benefit in patients with CRS, but the evidence remains preliminary due to limited sample size and substantial heterogeneity. Larger randomized controlled trials with standardized protocols are required to validate these findings and to define the clinical role of photobiomodulation in CRS management.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.