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Duration of music listening in music-induced analgesia: A pilot randomized controlled trial

van der Valk Bouman ES, Becker AS, Smienk M, Horstink MMB, de Vos CC, Jeekel H, De Zeeuw CI, Klimek M

Complementary therapies in medicine · 0 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Universidad u hospital
Erasmus Medisch Centrum
Universidad u hospital
Erasmus MC University Medical Center Rotterdam

Según 2 financiadores declarados.

Publicación

Publicado
2025-11-26 · Complement Ther Med · vol. 96 · pág. 103311
Editorial
Elsevier BV
Citado
1 cita · más que el 84% de estudios similares · 1.1× el promedio de su campo
Referencias
40 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Music Therapy and Health · Pain Management and Placebo Effect · Neuroscience and Music Perception
Palabras clave
pain threshold, pain tolerance, pain intensity, pain unpleasantness, emotional valence, heart rate variability, sympathetic activity, non-pharmacological pain management
MeSH
humans, pain measurement, music therapy, analgesia, pilot projects, pain threshold, heart rate, music, adult, middle aged, female, male, young adult, pain management

8 autores

  • Emy S. van der Valk Bouman🇳🇱Erasmus MC
  • Antonia S. Becker🇳🇱 · autor de correspondenciaErasmus MC
  • Melissa Smienk🇳🇱Erasmus MC
  • M. M. B. Horstink🇳🇱Maasstad Ziekenhuis
  • Cecile C. de Vos🇳🇱Erasmus MC
  • Hans J. Jeekel🇳🇱Erasmus MC
  • Chris I. De Zeeuw🇳🇱Netherlands Institute for Neuroscience; Royal Netherlands Academy of Arts and Sciences; Erasmus MC
  • Markus Klimek🇳🇱Erasmus MC

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Music is a non-pharmacological treatment that is effective for pain relief. However, the extent to which duration of listening to music influences music-induced analgesia (MIA) is unclear.

Methods

In this pilot randomized controlled trial, healthy volunteers (n = 80) were subjected in a parallel design to music for 0, 1, 5 or 20 min. Pain was induced by increasing electric stimuli using the Biopac program Stimusol. MIA was assessed at baseline, at the end of the experimental period with music (intervention), and after a five-minute washout period without music. Data were analyzed using linear mixed models to account for measurement sequences.

Results

For the intervention measurement, pain endurance did not differ between groups. However, pain threshold was higher in the 20-minute group (β = 2.5, p < 0.001), but not in the 1-minute and 5-minute groups, compared to the control group. On average, perceived pain intensity and unpleasantness were somewhat lower in all music groups compared to the control group, but none of these differences were significantly different. Emotional valence was higher in the music groups compared to the control group, which was significant only for the 1-minute group (β = 0.6, p = 0.027). Albeit not consistently, heart rate variability indicated more sympathetic activity in all music groups. For the washout measurement, no clear trends were visible.

Conclusion

Translating these findings to clinical care, it seems advisable for patients to listen to music for a sufficient amount of time (≥20 min) to achieve effective MIA. Further research is needed to validate these results and determine the optimal "dosage" for MIA.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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