Changes in erythrocyte fatty acid profile after 12 weeks of omega-3 fatty acid (EPA+DHA) supplementation and endurance training in amateur runners
Tomczyk M, Kowalska A, Dzitkowska-Zabielska M, Calder PC, Fisk HL, Kulczyński B, Antosiewicz J
Prostaglandins, leukotrienes, and essential fatty acids · 1 cita
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Narodowe Centrum Nauki
- Gobierno
- National Science Centre Poland
- Subvenciones
- Narodowe Centrum Nauki (2018/31/N/NZ7/02962)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2025-10-01 · Prostaglandins Leukot Essent Fatty Acids · vol. 208 · pág. 102710
- Editorial
- Elsevier BV
- Citado
- 1 cita · más que el 69% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 72 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC-ND
- Áreas de investigación
- Fatty Acid Research and Health · Exercise and Physiological Responses · Muscle metabolism and nutrition
- Palabras clave
- omega-3 supplementation, EPA, docosahexaenoic acid, endurance training, recreational runners, omega-3 index, arachidonic acid, monounsaturated fatty acids, docosapentaenoic acid, exercise and lipid metabolism
- MeSH
- erythrocytes, humans, fatty acids, omega-3, docosahexaenoic acids, eicosapentaenoic acid, fatty acids, physical endurance, running, dietary supplements, adult, middle aged, female, male, endurance training
7 autores
- Maja Tomczyk🇵🇱Gdansk University of Physical Education and Sport
- Agnieszka Kowalska🇵🇱Gdansk University of Physical Education and Sport
- Magdalena Dzitkowska-Zabielska🇵🇱Gdansk University of Physical Education and Sport
- Philip C. Calder🇬🇧University Hospital Southampton NHS Foundation Trust; NIHR Southampton Biomedical Research Centre; University of Southampton
- Helena L. Fisk🇬🇧University Hospital Southampton NHS Foundation Trust; NIHR Southampton Biomedical Research Centre; University of Southampton
- Bartosz Kulczyński🇵🇱Poznań University of Life Sciences
- Jędrzej Antosiewicz🇵🇱Gdańsk Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Fatty acid (FA) profiles can be examined in both plasma and red blood cells (RBCs), with the latter showing the average FA concentrations over the past 3-4 months and not being susceptible to daily fluctuations dependent on diet or supplementation. This study provides data on changes in the FA profile in RBCs as a result of 12 weeks supplementation with long chain omega-3 polyunsaturated fatty acids (n-3 PUFAs; EPA and DHA) and training intervention in amateur runners. The study included 26 amateur runners, 14 of whom were assigned to the n-3 PUFA supplementation group (2234 mg of EPA and 916 mg of DHA daily) and 12 to the placebo group; both groups underwent the exercise training. After the 12-week intervention, runners taking n-3 PUFAs showed statistically significant increases in EPA, docosapentanoic acid, DHA and total PUFAs, and decreases in lignoceric, palmitoleic, vaccenic, gondoic, linoleic, eicosadienoic, dihomo-γ-linolenic, and arachidonic acids compared to placebo group. In addition, increases in omega-3 index, delta 9-desaturase index (C16), and PUFA/MUFA index, and a decrease in monounsaturated fatty acids (MUFAs) and AA/EPA ratio was observed. There were no changes in RBC FAs in the placebo group indicating that exercise training had no effect on RBC FAs. This study provides novel insights into the changes in FA profile in RBCs with n-3 PUFA supplementation, the importance of which in both sports and health scenarios requires further research.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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