Nut consumption and risk of cardiovascular disease events and all-cause mortality: A systematic review and dose-response meta-analysis of prospective cohort studies
Liu M, Wang M, Fu X, He X, Wang M, Su Y, Liu G, Hu F, Zhang M, Zhao Y, Hu D
Archives of cardiovascular diseases · 1 cita
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Organización sin fines de lucro
- Postdoctoral Research Foundation of China
- Gobierno
- Shenzhen Science and Technology Innovation Program
- Gobierno
- Basic and Applied Basic Research Foundation of Guangdong Province
- Subvenciones
- Basic and Applied Basic Research Foundation of Guangdong Province (2022A1515010503); National Natural Science Foundation of China (82273707); Shenzhen Science and Technology Innovation Program (JCYJ20220818095818040); National Natural Science Foundation of China (82103940); Basic and Applied Basic Research Foundation of Guangdong Province (2021A1515012503); Postdoctoral Research Foundation of China (2021M692903); National Natural Science Foundation of China (82304228); National Natural Science Foundation of China (81973152); Shenzhen Science and Technology Innovation Program (JCYJ20210324093612032); National Natural Science Foundation of China (82073646)
Según 4 financiadores declarados.
Publicación
- Publicado
- 2025-09-23 · Arch Cardiovasc Dis · vol. 119 · número 3 · págs. 216–232
- Editorial
- Elsevier BV
- Citado
- 1 cita · más que el 47% de estudios similares · 0.3× el promedio de su campo
- Referencias
- 71 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Botany, Ecology, and Taxonomy Studies · Antioxidant Activity and Oxidative Stress
- Palabras clave
- Nut, Prospective cohort study, Disease, Consumption (sociology), Cohort study, Epidemiology, Risk factor, Atherosclerotic cardiovascular disease
- MeSH
- humans, nuts, cardiovascular diseases, prognosis, cause of death, risk assessment, risk factors, nutritive value, time factors, adult, aged, middle aged, female, male, protective factors, diet, healthy, heart disease risk factors
12 autores
- Mengna Liu🇨🇳Zhengzhou University
- Mengmeng Wang🇨🇳Zhengzhou University
- Xueru Fu🇨🇳Zhengzhou University
- Xinxin He🇨🇳Zhengzhou University
- Mengdi Wang🇨🇳Zhengzhou University
- Yijia Su🇨🇳Zhengzhou University
- Ge Liu🇨🇳Zhengzhou University
- F. B. Hu🇨🇳Shenzhen University Health Science Center
- Fulan Hu🇨🇳 · autor de correspondenciaShenzhen University Health Science Center
- Ming Zhang🇨🇳Zhengzhou University; Shenzhen University Health Science Center
- Yang Zhao🇨🇳 · autor de correspondenciaZhengzhou University
- Dongsheng Hu🇨🇳 · autor de correspondenciaZhengzhou University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Evidence for the effects of nut consumption on cardiovascular disease (CVD) events and all-cause mortality has been reported inconsistently.
Aims
To assess the associations between nut consumption and CVD events and all-cause mortality.
Methods
We searched the Web of Science, Embase and PubMed up until 24 October 2023. In order to compute relative risks (RRs) and 95% confidence intervals (CIs), random-effects models were employed. Restricted cubic splines were performed to explore potential linear or non-linear associations. Heterogeneity was assessed (Cochran Q statistic) and quantified (I2-statistic). NutriGrade assessed the certainty of the evidence.
Results
Thirty-three publications (63 studies) were included. Comparisons between individuals with the highest versus lowest intake of nuts resulted in RRs (95% CIs) for coronary heart disease (CHD), stroke, CVD, CVD mortality and all-cause mortality of 0.81 (0.75-0.87), 0.91 (0.84-0.99), 0.86 (0.82-0.91), 0.74 (0.70-0.78) and 0.77 (0.73-0.81), respectively. With per 28-g increases in weekly nut intake, the RRs (95% CIs) for CHD, stroke, CVD, CVD mortality and all-cause mortality were 0.96 (0.95-0.97), 0.99 (0.97-1.01), 0.98 (0.97-0.99), 0.90 (0.86-0.94) and 0.92 (0.90-0.94), respectively. Nut intake was linearly associated with incidence of stroke (Pnon-linearity=0.691), CVD (Pnon-linearity=0.101) and CVD mortality (Pnon-linearity=0.069) and non-linearly associated with CHD (Pnon-linearitynon-linearity<0.001).
Conclusions
This systematic review and meta-analysis revealed an association between nut consumption and reduced risk of CVD and all-cause mortality. It highlighted the importance of nuts as a dietary supplement in the primary prevention of CVD and all-cause mortality.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.