Effects of Four Weeks of Alternate-Day Fasting with or Without Protein Supplementation-A Randomized Controlled Trial
Pang BWJ, Yang Y, Rashiqah N, Huang CB, Sim DW
Nutrients · 1 cita
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Nanyang Technological University
- Universidad u hospital
- National Institute of Education, Nanyang Technological University
- Universidad u hospital
- Physical Education and Sports Science Final Year Project Fund for consumables
Según 3 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-11-25 · Nutrients · vol. 17 · número 23 · pág. 3691
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 0 citas · más que el 34% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 41 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Muscle metabolism and nutrition
- Palabras clave
- Bioelectrical impedance analysis, Randomized controlled trial, Weight loss, Whey protein, Blood pressure, Intermittent fasting, Fat mass, Body weight
- MeSH
- humans, obesity, weight loss, blood glucose, dietary proteins, body mass index, fasting, body composition, blood pressure, dietary supplements, adult, male, young adult, whey proteins
5 autores
- Benedict Wei Jun Pang🇸🇬Nanyang Technological University; Geriatric Education and Research Institute
- Yifan Yang🇸🇬 · autor de correspondenciaNanyang Technological University
- Nur Rashiqah🇸🇬Nanyang Technological University
- Christopher Huang🇸🇬Nanyang Technological University
- D. W. Sim🇸🇬Nanyang Technological University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background/Objectives: Long-term alternate-day fasting (ADF) effectively combats obesity, but its short-term effects are less clear. Like other diets, ADF-induced weight loss often includes muscle loss, and whether protein supplementation mitigates this is uncertain. This study examined the effects of short-term ADF on body composition and health and whether protein supplementation preserves muscle mass during weight loss in young Asian men with an unhealthy BMI (≥23.0 kg/m2). Methods: Twenty participants were recruited for a single-arm trial to address the first objective, and twenty-six participants were randomly assigned to a control (C) or protein group (P) in a follow-up trial to address the second objective. The participants alternated between feeding (ad libitum) and fasting (400-600 kcal consumed between 12 and 2 PM) days for four weeks. The participants in P consumed 25 g of whey protein as part of the fasting-day meal. Pre-post body composition was assessed using bioelectrical impedance analysis. Anthropometry, fasting blood glucose (FG), and resting blood pressure (BP) were measured weekly. Results: Since interaction effects were absent, data from all three groups were combined for analyses. Four weeks of ADF significantly (p p = 0.753-0.919). No significant differences were detected between the C and P groups for any of the measures. Conclusions: Short-term ADF effectively reduced body and fat mass, but it also reduced muscle mass, and this reduction was not attenuated by low-dose protein supplementation (25 g) during fasting days. Future studies should explore the effectiveness of protein or leucine supplementation, throughout the feeding and fasting days, in terms of preserving muscle during weight loss.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.