Beyond strength: dietary nitrate augments self-selected functional mobility after resistance training in middle-aged adults
Peoples BM, McIntosh MC, Harrison KD, Smith BR, Guzman KGS, Campos-Vargas SE, Cifuentes DC, Mueller BJ, Kavazis AN, Beck DT, Roberts MD, Roper JA
GeroScience · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Science Foundation
- Universidad u hospital
- Auburn University
- Universidad u hospital
- Edward Via College of Osteopathic Medicine
- Gobierno
- National Institutes of Health
- Subvenciones
- National Institutes of Health (5t32gm141739-02); National Institutes of Health (1t32tr004767-01); National Science Foundation (2230971)
Según 4 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-12-18 · Geroscience · vol. 48 · número 5 · págs. 7325–7340
- Editorial
- Springer International Publishing
- Citado
- 0 citas · más que el 37% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 49 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Balance, Gait, and Falls Prevention · Cardiovascular and exercise physiology · Muscle metabolism and nutrition
- Palabras clave
- dietary nitrate, beetroot juice, resistance training, functional mobility, walking speed, middle-aged adults, older adults, inactive adults, Timed Up and Go test, 6-minute walk test, sex differences, exercise supplementation
- MeSH
- humans, beta vulgaris, nitrates, gait, pilot projects, double-blind method, dietary supplements, middle aged, female, male, resistance training, fruit and vegetable juices
12 autores
- Brandon M. Peoples🇺🇸Auburn University
- Mason C. McIntosh🇺🇸Auburn University
- Kenneth D. Harrison🇺🇸Auburn University
- Bria R. Smith🇺🇸Auburn University
- Keven Santamaría-Guzmán🇺🇸Auburn University
- Silvia E. Campos-Vargas🇺🇸Auburn University
- Damaris C. Cifuentes🇺🇸Auburn University
- Breanna J. Mueller🇺🇸Auburn University
- Andreas N. Kavazis🇺🇸Auburn University
- Darren T. Beck🇺🇸Auburn University; Edward Via College of Osteopathic Medicine
- Michael D. Roberts🇺🇸Auburn University
- Jaimie A. Roper🇺🇸 · autor de correspondenciaAuburn University
Resumen
El texto original del estudio, en el idioma en que se publicó.
This study aimed to assess whether dietary nitrate supplementation with resistance training (RT) augments gait performance and functional mobility in inactive middle-aged and older adults. We hypothesized that combining nitrate-rich beetroot juice (BRJ) with RT would yield improvements in gait and functional mobility compared to RT with nitrate-depleted beetroot juice placebo (PLA) supplementation. In this 12-week, randomized, double-blind, placebo-controlled pilot trial, 28 healthy, inactive adults (56 ± 7 years) were assigned to either a BRJ (~ 12.8 mmol nitrate/day) or PLA group while completing a supervised, full-body RT program (2×/week). Pre- and post-intervention assessments included the instrumented stand and walk (iSAW), 6-min walk test (i6MWT), and timed up and go (iTUG) tests. Supplement adherence, training compliance, and volume were equivalent between groups. ANCOVA analyses controlling baseline values revealed significant between-group differences favoring the BRJ group for gait speed (adjusted means: 1.38 vs 1.27 m/s, p = .010), stride length (p .05). In our middle-aged sample, supplementing dietary nitrate alongside RT led to clinically meaningful improvements in functional mobility during self-selected conditions, exceeding the gains from 12 weeks of twice-weekly RT alone. Preliminary descriptive analyses revealed sex-specific group-level differences that might suggest emerging trends. Although no inferential statistics were conducted, the patterns provide potential directions for future research investigating the effects of RT in middle-aged adults.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.