Egg Consumption and Cognitive Function: A Systematic Review and Dose-Response Pooled Analysis Exploring Optimal Daily Intake
Liu J, Shen Q, Wang X
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 0 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Peking University
- Universidad u hospital
- Innovation Fund for Outstanding PhD Candidates of Peking University Health Science Centre
Según 2 financiadores declarados.
Publicación
- Publicado
- 2026-01-06 · J Hum Nutr Diet · vol. 39 · número 1 · pág. e70198
- Editorial
- Wiley
- Citado
- 2 citas · más que el 93% de estudios similares · 5.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 62 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nutritional Studies and Diet · Nutrition and Health in Aging · Child Nutrition and Water Access
- Palabras clave
- Pooled analysis, Cognition, Consumption (sociology), Food intake, Meta-analysis, Food consumption
- MeSH
- humans, diet, longitudinal studies, cross-sectional studies, cognition, eating, eggs, aged, middle aged, female, male, cognitive dysfunction
3 autores
- J Liu🇨🇳Peking University
- Qingqing Shen🇨🇳Linyi University
- Xinxin Wang🇨🇳 · autor de correspondenciaLinyi University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Eggs provide a high amount of protein and micronutrients. However, the effects of egg intake on cognitive function remain inconclusive, and there has not yet been a pooled analysis on this topic.
Methods
Literature was searched from EMBASE, PubMed, MEDLINE, Web of Science, and Scopus database until 11 November 2025. Pooled risk ratios (RRs) were calculated utilising random-effects models. The heterogeneity among studies was evaluated using Q and I2 statistics. Subgroup analysis and meta-regression were used to assess the impact of ages, follow-up years of longitudinal studies, diet assessment and risk of bias. Sensitivity analyses were conducted to evaluate the robustness, and publication bias was assessed through Egger's tests. Dose-response relationships were explored through a one-stage robust error meta-regression model. This systematic review and meta-analysis were registered at PROSPERO (No. CRD42024613229).
Results
We identified 13 longitudinal and 8 cross-sectional studies, comprising 99,453 individuals with 18,893 cases mainly from Asian countries and the United States. Egg consumption closest to 50 g/day was longitudinally linked to a lower risk of cognitive decline (pooled RR = 0.91; 95%CI = 0.83-0.99), and a 'U-shaped' dose-response relationship was also observed at the lowest risks occurring at 50-60 g/day of egg. Stratified by ages, follow-up years, study population and egg intake assessment, the similar 'U-shaped' relationships were also observed. No publication bias was detected.
Conclusion
One egg/day (50-60 g/day) is necessary to maintain healthy cognition function in elderly, which may be an effective food therapy to alleviate cognitive decline.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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