Music Therapy Versus Cognitive Behavioral Therapy via Telehealth for Anxiety in Survivors of Cancer: A Randomized Clinical Trial
Liou KT, Bradt J, Currier MB, Baser R, Panageas K, MacLeod J, Walker D, Li SQ, Lopez AM, McConnell K, Mao JJ
Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 3 citas
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Cómo se estudió
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- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Posiblemente financiado por la industria
- Gobierno
- NCI NIH HHS
- Autores
- Al menos un autor declara un vínculo económico con la industria
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2026-01-06 · J Clin Oncol · vol. 44 · número 5 · págs. 375–385
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 8 citas · más que el 100% de estudios similares · 70.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 62 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Music Therapy and Health · Cancer survivorship and care · Art Therapy and Mental Health
- Palabras clave
- music therapy, cognitive behavioral therapy, cancer survivors, anxiety, telemedicine, non-inferiority, comparative effectiveness, Hospital Anxiety and Depression Scale, fatigue, depression, insomnia, health-related quality of life
- MeSH
- humans, neoplasms, treatment outcome, music therapy, anxiety, telemedicine, quality of life, adult, aged, middle aged, female, male, cancer survivors, cognitive behavioral therapy
11 autores
- Kevin T. Liou🇺🇸Memorial Sloan Kettering Cancer Center
- Joke Bradt🇺🇸Drexel University
- M. Beatriz Currier
- Raymond E. Baser🇺🇸Memorial Sloan Kettering Cancer Center
- Katherine Panageas🇺🇸Memorial Sloan Kettering Cancer Center
- Jodi MacLeod
- Desiree A. H. Walker🇺🇸Young Survival Coalition
- Susan Q. Li🇺🇸Memorial Sloan Kettering Cancer Center
- Ana María López🇺🇸Thomas Jefferson University
- Kelly McConnell🇺🇸Memorial Sloan Kettering Cancer Center
- Jun J. J. Mao🇺🇸Memorial Sloan Kettering Cancer Center
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Anxiety is prevalent, disruptive, and undertreated among survivors of cancer. Cognitive behavioral therapy (CBT) is the first-line treatment, but not all individuals have access, respond to treatment, or prefer this option because of stigma. Music therapy is effective for short-term anxiety reduction, but it is unknown whether it is noninferior to first-line CBT for long-term anxiety reduction.
Methods
This comparative effectiveness trial randomly assigned English- or Spanish-speaking survivors of cancer to seven weekly telehealth sessions of music therapy or CBT. The coprimary end points were changes in the Hospital Anxiety and Depression Scale (HADS) anxiety score at weeks 8 and 26. The noninferiority margin was 0.35 standard deviations, informed by a minimal clinically important difference (MCID) of 1.7 points. Secondary outcomes included fatigue, depression, insomnia, pain, cognitive dysfunction, and health-related quality of life.
Results
Among N = 300 patients, 74.7% was female, 76.5% was White, and 19.0% was Hispanic. At week 8, the mean change in HADS anxiety score was -3.12 (95% CI, -3.59 to -2.65) in music therapy and -2.97 (95% CI, -3.45 to -2.50) in CBT; the between-group difference was -0.15 (95% CI, -0.78 to 0.49), within the noninferiority margin of 1.20 (P P < .001). Both groups produced anxiety reductions exceeding the MCID and showed similar improvements in secondary outcomes.
Conclusion
Music therapy is noninferior to CBT for anxiety in survivors of cancer. Both telehealth interventions produced clinically meaningful, durable improvements in anxiety.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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