Effects of Caloric Restriction Combined With Exercise on Lipid Metabolism and Blood Pressure: A Systematic Review and Network Meta-Analysis
Hei Y, Xie Y
Nutrition reviews · 0 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2025-10-12 · Nutr Rev · vol. 84 · número 10 · págs. 2014–2027
- Editorial
- Oxford University Press
- Citado
- 0 citas · más que el 40% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 140 trabajos
- Acceso
- De pago
- Áreas de investigación
- Cardiovascular and exercise physiology · Physical Activity and Health · Blood Pressure and Hypertension Studies
- Palabras clave
- caloric restriction, physical activity, resistance training, aerobic exercise, lipid metabolism, blood pressure, cholesterol, cardiovascular health, intervention duration
- MeSH
- humans, exercise, caloric restriction, blood pressure, lipid metabolism, randomized controlled trials as topic
2 autores
- Yang Hei🇨🇳Qilu Medical University
- Yongchao Xie🇨🇳 · autor de correspondenciaGuiyang Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Context
Caloric restriction (CR) combined with exercise has been shown to significantly improve cardiovascular health; however, the synergistic effects of different exercise modalities with CR remain unclear.
Objective
In this network meta-analysis we aimed to compare the effects of resistance (RE), aerobic (AE), and mixed (MIX) exercise combined with CR on lipid metabolism and blood pressure to identify the most effective intervention strategy and provide evidence-based recommendations for cardiovascular health improvement.
Data sources
We systematically searched relevant studies published January 2007 to September 2024 in PubMed, Web of Science, Embase, and the Cochrane Library.
Data extraction
Randomized controlled trials (RCTs) examining CR combined with different exercise types were included in this analysis. Data were extracted on study characteristics, intervention details, and outcome indicators. The Cochrane Collaboration risk of bias tool was used to evaluate methodological quality.
Data analysis
Standardized mean differences (SMDs) with 95% CIs were calculated using a random-effects model. Subgroup analyses were performed based on study characteristics, methodological factors, and intervention duration.
Conclusions
When the intervention duration is ≤16 weeks, mixed exercise combined with CR exhibits the highest probability of yielding optimal improvements in blood lipids, cholesterol, and blood pressure. For interventions exceeding 16 weeks, aerobic exercise with CR is most likely to produce the greatest improvements in blood lipids and cholesterol. For improving blood pressure, mixed exercise combined with CR consistently shows a higher probability of being the most effective intervention compared to other approaches.
Systematic review registration
PROSPERO registration No. [CRD42025632306].
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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