A Brief Web-Based and Mobile Intervention of Intermittent Fasting With Meal Support for Weight Loss Among Adults With Overweight and Obesity in Japan: Pilot Randomized Controlled Trial
Noda T, Shimamoto T, Kiyohara K, Imanaka M, Nishioka N, Tateyama Y, Iwami T
JMIR mHealth and uHealth · 0 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiado por la industria
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2025-10-01 · JMIR Mhealth Uhealth · vol. 14 · pág. e58930
- Editorial
- JMIR Publications
- Citado
- 0 citas · más que el 25% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 40 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Mobile Health and mHealth Applications · Nutrition, Health and Food Behavior
- Palabras clave
- intermittent fasting, weight loss, obesity, overweight, meal replacement, very low calorie diet, online intervention, mobile health, online guidance, body composition, fat mass, fat-free mass, metabolic biomarkers, blood pressure, quality of life, physical activity, intervention adherence, feasibility, safety, Japan, adults, university students, office workers, healthcare workers, healthy lifestyle promotion
- MeSH
- humans, obesity, weight loss, body mass index, fasting, pilot projects, internet, adult, middle aged, japan, female, male, overweight, mobile applications, internet-based intervention, intermittent fasting
7 autores
- Takashi Noda🇯🇵Kyoto University
- Tomonari Shimamoto🇯🇵Kyoto University
- Kosuke Kiyohara🇯🇵Otsuma Women's University
- Mie Imanaka🇯🇵Shimane University; University of Shimane
- Norihiro Nishioka🇯🇵Kyoto University
- Yukiko Tateyama🇯🇵Kyoto University
- Taku Iwami🇯🇵Kyoto University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Intermittent fasting emerges as a promising dietary approach against obesity, offering a cost-effective strategy for implementation via web-based platforms. We developed a Brief Online Intermittent Fasting Program (OIF), featuring a self-administered, weekly 1-day fasting regimen with replacement meals delivery, online guidance, and app messaging to support adherence.
Objective
This pilot study aimed to assess the preliminary effectiveness, feasibility, and safety of the OIF on weight loss in adults with overweight and obesity in Japan. Secondary objectives were to assess its effects on body composition and metabolic markers.
Methods
This 12-week, 1:1 randomized controlled trial recruited adults with overweight and obesity (BMI from 23 to 1c, triglycerides, and cholesterol), quality of life, physical activity, intervention adherence, and adverse events.
Results
A total of 57 individuals were enrolled (28 in the intervention group and 29 in the control group). At 12 weeks, 25 participants in the intervention group and 27 participants in the control group completed follow-up. The baseline median weight was 75.8 (IQR 68.3-80.6) kg for the intervention group and 74.8 (IQR 69.8-81.8) kg for the control group. The mean weight change was -0.9 (SD 1.9) kg in the intervention group and +0.6 (SD 1.4) kg in the control group. The adjusted between-group difference in weight change was statistically significant at -1.6 (95% CI -2.5 to -0.8) kg. Fat mass change was not statistically significant (-0.1, 95% CI -1.3 to 1.4 kg), but muscle mass reduction was implied (-1.3, 95% CI -2.5 to -0.2 kg). Intervention adherence was 79% (22/28) in the intervention group. No serious adverse events were reported, and there were no significant changes in key biomarkers, such as hemoglobin A1c or quality of life.
Conclusions
The OIF demonstrated effectiveness in promoting modest weight loss among adults with overweight and obesity over 12 weeks, with high feasibility and safety indicated by low dropout rates and absence of serious adverse events. However, the observed reduction in muscle mass indicates a need for program refinement, such as incorporating exercise guidance, to optimize health outcomes.
Trial registration
UMIN-CTR UMIN000050437; https://tinyurl.com/4x5h2t2x.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.