Exploring the efficacy of repeated low-level red-light therapy in retarding childhood myopia progression: updated systematic review and meta-analysis
Liu C, Zhou Y, Zhan Z, Li X
Frontiers in medicine · 0 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2026-01-22 · Front Med (Lausanne) · vol. 13 · pág. 1713885
- Editorial
- Frontiers Media
- Citado
- 0 citas · más que el 4% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 50 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Ophthalmology and Visual Impairment Studies · Laser Applications in Dentistry and Medicine · Corneal surgery and disorders
- Palabras clave
- MEDLINE, Population, Quality of life (healthcare), Clinical trial, Disease
4 autores
- Chen Liu
- Yating Zhou🇨🇳Shanghai University of Traditional Chinese Medicine; Traditional Chinese Medicine Hospital of Kunshan
- Zongyue Zhan
- Xiaofeng Li · autor de correspondencia
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Due to the increasing prevalence of childhood myopia, low-level red-light therapy has surfaced as a non-pharmacological method to mitigate its advancement. This systematic review and meta-analysis evaluates the efficacy of repeated low-level red-light (RLRL) in pediatric populations, providing evidence-based support for its therapeutic usage.
Methods
A search was performed in PubMed, Web of Science, Cochrane Library, Embase, and prominent Chinese databases, including CNKI, VIP, and Wanfang, from their inception until May 13, 2025. This meta-analysis includes randomized controlled trials (RCTs) that matched the inclusion criteria and was analyzed using Stata software, version 18.0.
Results
This meta-analysis included 1,053 participants: 515 in the RLRL and 538 in the control groups. The SMD for SER reduction was 0.84 (95% CI: 0.50, 1.19), SMD for AL reduction was -1.01, (95% CI: -1.60, -0.41), and SMD for SFChT rise was 0.81 (95% CI: 0.65-0.98). There is no major publishing bias.
Conclusion
The meta-analysis found that children with myopia who got RLRL therapy in addition to normal treatment had significantly slower disease progression than the control group.
Systematic review registration
https://www.crd.york.ac.uk/PROSPERO/view/CRD420251034037, PROSPERO 2025 CRD420251034037.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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