The Effects of Time-Restricted Feeding and Exercise on Cardiometabolic Health in Sedentary Older Adults: A Randomized Controlled Trial
Peng L, Chen L, Xia J, Zhou J, Shi N, Cheng R, Shu L, Huang J, Hu M, Liao J
Medicine and science in sports and exercise · 1 cita
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Natural Science Foundation of Guangdong Province
- Gobierno
- National Key Research and Development Program of China
- Gobierno
- Nature Science Foundation of Guangdong Province
- Gobierno
- Program for Key Research Areas of University in Guangdong Province
Según 4 financiadores declarados.
Publicación
- Publicado
- 2026-03-02 · Med Sci Sports Exerc · vol. 58 · número 7 · págs. 1337–1351
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 1 cita · más que el 90% de estudios similares · 4.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 0 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC-ND
- Áreas de investigación
- Dietary Effects on Health · Cardiovascular and exercise physiology · Physical Activity and Health
- Palabras clave
- time-restricted feeding, exercise training, cardiometabolic health, sedentary older adults, heart rate variability, flow-mediated dilation, body composition, inflammatory markers, dietary adherence, lifestyle intervention
- MeSH
- humans, blood glucose, exercise, body composition, blood pressure, heart rate, middle aged, female, male, biomarkers, sedentary behavior, intermittent fasting
10 autores
- Linyu Peng🇨🇳Guangzhou Sport University; Guangzhou Huanan Business College
- L Chen🇨🇳Guangzhou Sport University
- Jingbo Xia🇨🇳Guangzhou Sport University
- Jie Zhou🇨🇳Guangzhou Sport University
- Niujin Shi🇨🇳Guangzhou Sport University
- RAN CHENG🇨🇳Guangzhou Sport University
- Linjie Shu🇨🇳Guangzhou Sport University
- Junhao Huang🇨🇳Guangzhou Sport University
- Min Hu🇨🇳 · autor de correspondenciaGuangzhou Sport University
- Jingwen Liao🇨🇳 · autor de correspondenciaGuangzhou Sport University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Exploring preferable lifestyle habits (diet and/or exercise) is essential in improving cardiometabolic health among older adults, who represent the most sedentary than other age populations and generally suffer from cardiometabolic problems. This study aimed to determine the effects of long-term time-restricted feeding (TRF), exercise training, and their combination on comprehensive measures of cardiovascular functions and multiple auxiliary indicators, and to simultaneously evaluate side effects and adherence.
Methods
Fifty-six sedentary participants (age: 57.6 ± 2.2) were randomly assigned to control (CON; n = 14), exercise (EX; n = 14), TRF (n = 14), and a combinational intervention (EX+TRF; n = 14) group. Participants in each group were instructed to follow their assigned TRF and/or exercise protocol throughout an 8-wk period. The primary outcomes were changes in cardiovascular functions. Secondary outcomes included changes in body composition, metabolic parameters, circulating biomarkers, eating habits, and nutrient intake.
Results
After 8 wks, EX (n = 11), TRF (n = 11), and EX+TRF (n = 14) produced significant increase in heart rate variability compared with CON (n = 11) ( P < 0.05); EX and EX+TRF also significantly improved flow-mediated dilation ( P < 0.05). TRF and EX+TRF significantly induced reductions in body fat percentage, lean mass, and total calorie consumption compared with CON ( P < 0.05); EX even induced significant increases in inflammatory biomarkers ( P < 0.05). Three interventions potentially caused adverse events but with no obvious difference; neither TRF nor EX produced superior adherence than the other, but there was lower compliance when counseling them both.
Conclusions
Sedentary older adults could achieve cardiovascular health benefits by choosing either TRF or exercise lifestyle, with no obvious difference in adverse events and adherence.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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