The impact of the multimodal neurologic enhancement music therapy intervention on clinical outcomes: A randomized trial of preterm infants hospitalized in the neonatal intensive care unit
Pivovarnik ES, Chen X, Evans EH
Early human development · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- University of Missouri
Según 1 financiador declarado.
Publicación
- Publicado
- 2026-03-14 · Early Hum Dev · vol. 218 · pág. 106534
- Editorial
- Elsevier BV
- Citado
- 0 citas · más que el 14% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 32 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Infant Development and Preterm Care · Music Therapy and Health · Neonatal and fetal brain pathology
- Palabras clave
- music therapy, preterm infants, extremely preterm infants, neonatal intensive care, neurologic injury, length of hospital stay, oxygen therapy duration, clinical outcomes
- MeSH
- humans, music therapy, length of stay, infant, newborn, infant, premature, intensive care units, neonatal, female, male, infant, extremely premature
3 autores
- Emily S. Pivovarnik🇺🇸 · autor de correspondenciaThe Ohio State University; University of Missouri
- Xianyan Chen🇺🇸University of Georgia
- Ellyn H. Evans🇺🇸University of Georgia; University of Missouri Health System; University of Missouri
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
This study evaluated the impact of Multimodal Neurologic Enhancement (MNE), a music therapy intervention, on clinical outcomes of preterm infants (< 34 weeks; N = 106) and a subgroup of extremely preterm infants (< 28 weeks; n = 20).
Method
A randomized trial was utilized, where infants were randomized to receive MNE or standard of care and matched based on gestational age at birth, sex, and neurologic injury. Infants in the MNE group received eight, 20-minute MNE sessions, beginning at 32 weeks post menstrual age (PMA). Analysis included negative binomial and linear regression, adjusting for relative covariates.
Principal results
Across the full cohort and the extremely preterm subgroup, there were no significant differences in PMA at discharge, duration of oxygen therapy (days), PMA at transition off oxygen therapy, or transition to full oral feeding (days). Among the extremely preterm subgroup, MNE was associated with a significantly shorter length of stay (days) (IRR = 0.81, corresponding to β̂ = -0.21; 95% CI for IRR: 0.68, 0.98).
Major conclusions
These findings suggest that MNE may offer targeted benefits for extremely preterm infants. This study highlights the potential of MNE as a safe, feasible intervention to support clinical outcomes during Neonatal Intensive Care Unit admission for preterm infants.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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