Blueberry consumption enhances vascular function but not cognitive abilities in healthy individuals: a systematic review and meta-analysis
He Y, Yang J, Zhang S, Mai J, Li M
Nutrition research (New York, N.Y.) · 0 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- National Key Research and Development Program of China
- Subvenciones
- National Key Research and Development Program of China (2023YFF1104203); National Natural Science Foundation of China (32472339)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2026-03-24 · Nutr Res · vol. 149 · págs. 162–177
- Editorial
- Elsevier BV
- Citado
- 1 cita · más que el 89% de estudios similares · 3.2× el promedio de su campo
- Referencias
- 53 trabajos
- Acceso
- De pago
- Áreas de investigación
- Phytochemicals and Antioxidant Activities · Neurological Disease Mechanisms and Treatments · Ginkgo biloba and Cashew Applications
- Palabras clave
- Mood, Cognition, Randomized controlled trial, Generalizability theory, Blood pressure, Effects of sleep deprivation on cognitive performance, Intervention (counseling)
- MeSH
- endothelium, vascular, humans, fruit, diet, affect, cognition, blood pressure, vasodilation, randomized controlled trials as topic, executive function, blueberry plants, vascular health
5 autores
- Yu He🇨🇳South China Agricultural University
- Jing Yang🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Shuzhen Zhang🇨🇳South China Agricultural University
- Junfan Mai🇨🇳South China Agricultural University
- Meiying Li🇨🇳 · autor de correspondenciaSouth China Agricultural University
Resumen
El texto original del estudio, en el idioma en que se publicó.
This systematic review and meta-analysis evaluated the effects of blueberry consumption on vascular and cognitive functions in healthy individuals. We hypothesized that blueberry consumption would improve vascular function and cognitive performance, so we analyzed 14 randomized controlled trials (RCTs) involving 632 participants. Results indicated that blueberry intervention significantly improved flow-mediated dilation (FMD) by 1.11% (95% CI: 0.50, 1.72; I² = 23%), suggesting a positive impact on vascular health. However, there were no significant changes in systolic blood pressure (SBP) (reduction of 0.11 mmHg; 95% CI: -2.82, 2.60; I² = 0%) or diastolic blood pressure (DBP) (reduction of 0.46 mmHg; 95% CI: -2.80, 1.87; I² = 0%). Cognitive outcomes showed no significant effect executive function (SMD: 0.21; 95% CI: -0.05, 0.46; I² = 42%) or mood (MD: 1.67; 95% CI: -1.35, 4.69; I² = 10%). The findings suggest that blueberries may enhance vascular function, but their impact on cognitive performance remains inconclusive. Limitations include heterogeneity in blueberry dosage, type, intervention duration, and participant age, which may affect the generalizability of the results. Future research should prioritize larger, well-designed randomized controlled trials with standardized protocols to confirm these findings and explore the mechanisms underlying the potential benefits of blueberries on vascular and cognitive health. This study provides preliminary evidence supporting the inclusion of blueberries in dietary strategies for cardiovascular health, while highlighting the need for further investigation into their cognitive effects.
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