Effect of photobiomodulation on pain relief and functional improvement in fractures: a systematic review and meta-analysis
Wang W, Xiu R, Zhao X, Qiu X, Tang L
Annals of medicine · 0 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2026-05-04 · Ann Med · vol. 58 · número 1 · pág. 2667061
- Editorial
- Informa
- Citado
- 0 citas · más que el 20% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 60 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Bone fractures and treatments · Biofield Effects and Biophysics
- Palabras clave
- low-level laser therapy, fracture, fracture pain, functional recovery, grip strength, bone regeneration, upper extremity fractures, mandibular fractures
- MeSH
- humans, pain, pain measurement, treatment outcome, fracture healing, fractures, bone, randomized controlled trials as topic, pain management, low-level light therapy
5 autores
- Weifeng Wang🇨🇳Chinese People's Liberation Army
- Ruijuan Xiu🇨🇳Chinese People's Liberation Army
- Xiaohua Zhao🇨🇳Chinese People's Liberation Army
- Xueling Qiu🇨🇳Chinese People's Liberation Army; Shandong First Medical University
- Lu Tang🇨🇳 · autor de correspondenciaChinese People's Liberation Army
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
Fractures, the most common type of trauma, can cause considerable distress to patients. Pain can not only affect the comfort of fracture patients but also delay their participation in rehabilitation training. Photobiomodulation (PBM) has been associated with pain reduction and the promotion of tissue healing. This systematic review and meta-analysis aimed to evaluate the efficacy of PBM in reducing pain and promoting rehabilitation in patients with fractures.
Methods
This study was registered on PROSPERO (CRD42024591373). We systematically searched PubMed, EMBASE, the Cochrane Library and Web of Science for RCTs that investigated PBM in fractures as of August 2025. The primary outcome was the pain score. The secondary outcomes included functional and healing.
Result
Finally, 12 and 9 studies were ultimately included in the systematic review and meta-analysis, respectively. The pooled analysis showed that the one-week pain score was lower in the PBM group than in the placebo group (MD -0.74, 95% CI -1.00, -0.47, p 2 = 0%). Subgroup analysis showed that the difference between the two groups was statistically significant regardless of fracture site or acupoint irradiation. Changes in pain scores were statistically significant in both groups at different wavelength combinations. The improvement in grip strength at 4 weeks was significantly greater in PBM than in placebo (MD 5.03, 95% CI 4.29, 5.78; p 2 = 0%). There were no significant differences in pain and functional scores at 4-26 weeks. Bone healing did not show differences between the two groups. No side effects reported.
Conclusion
PBM appears to relieve short-term pain in fractures and improve grip strength in patients with upper limb fractures, but does not show significant long-term benefits. Evidence for mandibular functional recovery and bone healing remains inconsistent. Future studies should determine therapeutic parameters and their impact on bone healing and long-term functional outcomes across fracture types.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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