Effects of different caffeine doses on fat oxidation and cardiovascular response during exercise at FATmax in overweight/obese female college students
Gong Z, Yu S, Lyu Z, Huang W, Zhang T
Journal of the International Society of Sports Nutrition · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2026-05-12 · J Int Soc Sports Nutr · vol. 23 · número 1 · pág. 2670558
- Editorial
- Springer Science+Business Media
- Citado
- 0 citas · más que el 37% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 36 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Coffee research and impacts · Cardiovascular and exercise physiology · Muscle metabolism and nutrition
- Palabras clave
- caffeine dose, fat oxidation, maximal fat oxidation, cardiovascular response, overweight and obesity, sedentary women, treadmill walking, substrate oxidation, carbohydrate oxidation, blood pressure, heart rate, caffeine dose-response, exercise metabolism, university students, appetite regulation, satiety
- MeSH
- humans, obesity, caffeine, exercise, double-blind method, oxidation-reduction, blood pressure, heart rate, dose-response relationship, drug, female, overweight, lipid metabolism, young adult
5 autores
- Zhigang Gong🇨🇳Jiangxi Normal University
- Shihong Yu🇨🇳Jiangxi Normal University
- Zhen Lyu🇨🇳Jiangxi Normal University
- Wenying Huang🇨🇳Jiangxi Normal University
- Tianou Zhang🇺🇸🇨🇱🇵🇪 · autor de correspondenciaUniversity of the Pacific; University of the Pacific; University of the Pacific
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
This study examined the acute effects of different caffeine doses on fat oxidation and cardiovascular responses at rest and during exercise at the intensity of maximal fat oxidation (FATmax) in overweight/obese sedentary female college students.
Methods
In a randomized trial, eleven participants (age: 20.2 ± 2.3 years; BMI: 26.36 ± 1.78 kg/m²) completed four conditions: placebo (cellulose) or caffeine at 3, 5, or 9 mg/kg. Each session comprised 60 min of seated rest followed by 40 min of treadmill walking at FATmax. Substrate oxidation (via indirect calorimetry), blood pressure, and the fingertip perfusion index (PI) were measured at specific time points: at rest (0, 30, and 60 min after capsule ingestion) and immediately post-exercise (100 min). Additionally, gas exchange and heart rate were recorded continuously throughout the entire 100-min session. Data were analyzed using SPSS 26.0 with two-way repeated-measures ANOVA (or Friedman test for non-normal data) and Bonferroni-adjusted post-hoc comparisons. Significance was set at p < 0.05.
Results
Caffeine did not alter the resting heart rate or substrate oxidation. During exercise, caffeine at 5 and 9 mg/kg significantly increased the heart rate and blood pressure (p p p p p < 0.05).
Conclusion
Acute caffeine intake at 3 and 5 mg/kg enhanced fat oxidation during FATmax exercise in sedentary overweight/obese females, whereas 9 mg/kg provided no additional metabolic benefit. However, the 5 mg/kg dose was associated with increased cardiovascular strain, which was not observed with the 3 mg/kg. Therefore, a dose of 3 mg/kg appears to offer an optimal balance between stimulating fat oxidation and maintaining cardiovascular safety in this population during acute exercise.
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