Lanzamiento Enero 2027

Ensayo controlado aleatorizado2026Financiación no declarada

Does adjunctive low-level laser therapy provide additional benefit following temporomandibular joint arthrocentesis with hyaluronic acid? A randomized clinical trial

Bahaa M, Azab AMFA, Elfarmawy MA, Morsi HO

Oral and maxillofacial surgery · 0 citas

Etiquetas de revisión

Financiación no declarada

Datos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2026-05-16 · Oral Maxillofac Surg · vol. 30 · número 1
Editorial
Springer Science+Business Media
Citado
0 citas · más que el 33% de estudios similares · 0.0× el promedio de su campo
Referencias
42 trabajos
Acceso
De pago
Áreas de investigación
Temporomandibular Joint Disorders · Laser Applications in Dentistry and Medicine · Salivary Gland Disorders and Functions
Palabras clave
low-level laser therapy, temporomandibular joint arthrocentesis, hyaluronic acid, anterior disc displacement without reduction, temporomandibular disorders, maximum mouth opening, jaw pain, adjunctive therapy
MeSH
humans, temporomandibular joint disorders, hyaluronic acid, pain measurement, treatment outcome, combined modality therapy, prospective studies, single-blind method, adult, female, viscosupplements, low-level light therapy, arthrocentesis, joint dislocations

4 autores

  • Moataz Bahaa🇪🇬British University in Egypt
  • Abdelrahman Mohamed Fahmy Abdelhameed🇨🇦 · autor de correspondenciaMcGill University
  • Mahmoud Ahmed Elfarmawy🇪🇬Suez University
  • Hesham O. Morsi🇪🇬British University in Egypt

Resumen

El texto original del estudio, en el idioma en que se publicó.

Purpose

This study aimed to evaluate whether adjunctive low-level laser therapy (LLLT) provides additional clinical benefit over an optimized arthrocentesis protocol with hyaluronic acid in patients with ADDwoR.

Materials and methods

From December 2022 to December 2023, a single-blinded prospective randomized clinical trial was conducted at The British University in Egypt's Department of Oral and Maxillofacial Surgery. The study involved 40 female participants diagnosed with Anterior Disc Displacement without Reduction (ADDwoR). Following TMJ arthrocentesis, subjects were assigned to one of two parallel cohorts: Group A received ten subsequent sessions of low-level laser therapy (LLLT), while Group B served as the control, receiving arthrocentesis alone. Treatment efficacy was evaluated based on pain intensity measured via a Visual Analogue Scale (VAS) and maximum mouth opening (MMO). Clinical assessments were performed at 2-week intervals over a 12-week follow-up period.

Results

No significant age-related differences were detected when comparing the intervention group to the control group (p = 0.087). No significant intergroup differences were observed in maximum mouth opening (MMO) or pain scores (VAS) at any follow-up time point (p > 0.05). Over the 12-week period, both study arms demonstrated significant clinical enhancement in terms of MMO and pain intensity (p < 0.001). Improvements in MMO were large in both groups, with postoperative values significantly higher than preoperative measurements. Pain scores decreased markedly following treatment, with preoperative scores significantly higher than all postoperative values. Overall, both interventions resulted in significant functional improvement and pain reduction, with no added benefit of the intervention over the control.

Conclusion

While both TMJ arthrocentesis alone and arthrocentesis supplemented with LLLT significantly improved maximum mouth opening and reduced pain, LLLT did not provide a significant incremental benefit over arthrocentesis with hyaluronic acid. These findings suggest that clinical improvements are primarily driven by the main intervention and may reflect a possible therapeutic ceiling effect, beyond which adjunctive LLLT does not confer measurable short-term benefit.

Clinical trial number

Not applicable.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

Confianza de la comunidad

Cargando…

¿Cuánto confías en los hallazgos de este estudio?

0 · nada10 · totalmente

Comentarios

¿Algo está mal aquí?

Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.

Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.