Combined Use of Personalized Music Intervention and Earplugs (MUSE) to Prevent Delirium in Mechanically Ventilated Patients: A Pilot Randomized Controlled Trial
Chen TJ, Lin YY, Wang AY, Traynor V, Frost SA, Chung YW, Lin CJ, Wu CR, Tu MC, Lai KS, Chiu HY
Clinical nursing research · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Taipei Medical University
- Universidad u hospital
- Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
- Universidad u hospital
- taipei medical university-shuang ho hospital, ministry of health and welfare
- Subvenciones
- Taipei Medical University (108FRP-06); Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare (108FRP-06)
Según 3 financiadores declarados.
Publicación
- Publicado
- 2026-05-23 · Clin Nurs Res · vol. 35 · número 6 · págs. 300–311
- Editorial
- SAGE Publishing
- Citado
- 0 citas · más que el 38% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 39 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Intensive Care Unit Cognitive Disorders · Music Therapy and Health · Nosocomial Infections in ICU
- Palabras clave
- earplugs, delirium prevention, mechanical ventilation, intensive care unit patients, sedation, pain, sleep, age as moderator
- MeSH
- humans, delirium, music therapy, respiration, artificial, pilot projects, ear protective devices, aged, middle aged, intensive care units, female, male
11 autores
- Ting‐Jhen Chen🇦🇺🇹🇼University of Wollongong; Taipei Medical University
- Yi‐Cheng Lin🇹🇼Taipei Medical University Hospital
- An‐Yi Wang🇦🇺🇹🇼Edith Cowan University; Wan Fang Hospital
- Victoria Traynor🇦🇺🇹🇼University of Wollongong; Taipei Medical University
- Steven Alfred Frost🇦🇺🇹🇼University of Wollongong; Liverpool Hospital; National Taiwan University Hospital; Ingham Institute
- Yi‐Wei Chung🇹🇼National Taiwan University Hospital
- Chia-Jou Lin🇹🇼Taipei Medical University
- Chia-Rung Wu🇹🇼Taipei Medical University
- Meng-Chun Tu🇹🇼Taipei Medical University Hospital; Taipei Medical University
- Kevin Shu-Leung Lai🇹🇼Taipei Medical University Hospital; Taipei Medical University
- Hsiao‐Yean Chiu🇹🇼 · autor de correspondenciaTaipei Medical University Hospital; Taipei Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Personalized music interventions and earplugs have shown promise in preventing intensive care unit (ICU) delirium, but evidence on their combined effects is limited. To evaluate the feasibility and preliminary effects of personalized music intervention combined with earplugs (MUSE) and personalized music intervention (PMI) on delirium prevention and clinical outcomes in mechanically ventilated patients. In this randomized controlled trial, 63 participants were assigned to MUSE, PMI, or usual care (UC). Delirium was assessed during each nursing shift using the Intensive Care Delirium Screening Checklist, alongside measures of pain, sedation, sleep, and clinical outcomes. The delirium incidence was 50% in the UC group, 25% in the PMI group, and 33% in the MUSE group. The median number of delirium or coma-free days was 7 (interquartile range [IQR] = 4-7) in the PMI group, 5 (IQR = 4-7) in the MUSE group, and 5 (IQR = 3-7) in the UC group. No significant between-group differences in either primary or secondary outcomes were identified. The exploratory post hoc subgroup analysis indicates that age may influence the effects of treatment on delirium. In this pilot study, neither MUSE nor PMI had significant effects in reducing delirium incidence among patients undergoing mechanical ventilation when compared with UC. However, PMI appeared more effective at preventing delirium relative to MUSE and UC, and the potential additional benefit of earplugs remains uncertain in this study. This study is registered at www.clinicaltrials.gov. Trial registration number is NCT04065256.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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