Effects of intensive lifestyle interventions with calorie-carbohydrate-restricted diet versus time-restricted eating on appetite and binge eating in type 2 diabetes: A randomized controlled trial
Mohammadpour S, Hadaegh F, Zayeri F, Hosseinpour-Niazi S, Badrooj N, Dankoob V, Shab-Bidar S, Mirmiran P
Appetite · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Shahid Beheshti University of Medical Sciences
Según 1 financiador declarado.
Publicación
- Publicado
- 2026-07-10 · Appetite · vol. 227 · pág. 108718
- Editorial
- Elsevier BV
- Citado
- 0 citas · más que el 52% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 60 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Eating Disorders and Behaviors · Regulation of Appetite and Obesity
- Palabras clave
- type 2 diabetes, intensive lifestyle intervention, time-restricted eating, appetite regulation, binge eating, hunger, satiety, desire to eat, prospective food consumption, obesity, overweight, structured exercise, behavioral education, information-motivation-behavioral skills model
- MeSH
- humans, diabetes mellitus, type 2, obesity, caloric restriction, feeding behavior, hunger, life style, appetite, bulimia, adult, aged, middle aged, female, male, overweight, diet, carbohydrate-restricted, intermittent fasting
8 autores
- Saba Mohammadpour🇮🇷National Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences
- Farzad Hadaegh🇮🇷Research Institute for Endocrine Sciences; Shahid Beheshti University of Medical Sciences
- Farid Zayeri🇮🇷Shahid Beheshti University; Shahid Beheshti University of Medical Sciences
- Somayeh Hosseinpour‐Niazi🇮🇷Research Institute for Endocrine Sciences; Shahid Beheshti University; Shahid Beheshti University of Medical Sciences
- Negin Badrooj🇮🇷Tehran University of Medical Sciences
- Vida Dankoob🇮🇷Tehran University of Medical Sciences
- Sakineh Shab‐Bidar🇮🇷🇬🇧 · autor de correspondenciaTehran University of Medical Sciences; University of Glasgow
- Parvin Mirmiran🇮🇷 · autor de correspondenciaResearch Institute for Endocrine Sciences; Shahid Beheshti University; Shahid Beheshti University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
The impact of intensive lifestyle interventions on appetite regulation and binge eating in individuals with type 2 diabetes (T2D) remains unclear. This study evaluated the effects of combined lifestyle interventions on appetite responses and binge eating in overweight or obese adults with T2D. In a randomized trial, 120 participants with T2D were allocated to three groups (n = 40 each): (1) Calorie-carbohydrate restriction (CCR), (2) Time-restricted eating with CCR (TRE + CCR), or (3) Control. Intervention groups received structured exercise and behavioral education based on the Information-Motivation-Behavioral Skills model. Appetite perceptions (hunger, satiety, desire to eat, and prospective food consumption) and binge eating (Binge Eating Scale; BES and objective binge episodes) were evaluated at baseline, week 12, and week 24 using linear mixed models. Both CCR and TRE + CCR significantly improved subjective appetite compared with the control group at 12 and 24 weeks (all p < 0.01). At 24 weeks, hunger decreased by -24.1 mm (95% CI: -35.8, -12.5) in the CCR group and -32.7 mm (95% CI: -44.2, -21.3) in the TRE + CCR group. Satiety also increased by 21.7 mm (95% CI: 9.46, 33.9) and 29.4 mm (95% CI: 17.4, 41.4), respectively. Significant reductions were observed for desire to eat and prospective food consumption. In contrast, changes in BES and objective binge episodes were not significantly different between groups at any time point. No significant differences were detected between the CCR and the TRE + CCR groups. Intensive lifestyle interventions incorporating CCR or TRE + CCR effectively reduced appetite in adults with T2D but did not significantly affect binge eating. Future research should target individuals with higher baseline BES scores to clarify potential benefits for binge eating behavior.
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