Effects of group-based music therapy combined with speech therapy on language and social skills in preschool children with autism spectrum disorder: An exploratory randomized controlled trial
Liu CE, Chen PY, Lai TJ, Yang SM
Research in developmental disabilities · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- National Taiwan University Hospital
- Universidad u hospital
- National Taiwan University Hospital Hsin-Chu Branch
- Universidad u hospital
- National Taiwan University Hospital Hsin-Chu Branch Hsin-Chu Hospital
Según 3 financiadores declarados.
Publicación
- Publicado
- 2026-07-17 · Res Dev Disabil · vol. 175 · pág. 105345
- Editorial
- Elsevier BV
- Citado
- 1 cita · más que el 98% de estudios similares · 8.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 28 trabajos
- Acceso
- De pago
- Áreas de investigación
- Music Therapy and Health · Autism Spectrum Disorder Research · Music Education and Analysis
- Palabras clave
- autism spectrum disorder, speech therapy, preschool children, language delay, social communication, early intervention, combination therapy, emotional and behavioral problems, parental stress, sensory difficulties, social interaction difficulties, Child Behavior Checklist, Parenting Stress Index-Short Form, multiple imputation, intention-to-treat analysis, false discovery rate
- MeSH
- humans, language development disorders, treatment outcome, combined modality therapy, music therapy, speech therapy, psychotherapy, group, child, preschool, female, male, social skills, autism spectrum disorder
4 autores
- Chih-En Liu🇹🇼National Taiwan University Hospital
- Peiying Chen🇹🇼National Taiwan University Hospital
- Ting-Ju Lai🇹🇼National Taiwan University Hospital
- Shu-Mei Yang🇹🇼 · autor de correspondenciaNational Taiwan University; National Taiwan University Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Autism spectrum disorder (ASD) is characterized by early difficulties in language and social communication. While speech therapy is a core early intervention, music therapy has been increasingly applied to support social-emotional development. However, evidence regarding the additive effects of group-based music therapy combined with speech therapy in preschool children with ASD remains limited.
Method
This exploratory randomized controlled trial enrolled (RCT) preschool children aged 3-5 years with ASD and language delay. Participants were randomly assigned to a Music Therapy group receiving group-based music therapy (60 min/week) plus individual speech therapy (30 min/week), or a Control group receiving speech therapy alone, for 8 weeks. The primary outcome was week 8 language performance assessed using the Preschool Language Scale (PLS). Secondary outcomes included autism-related characteristics, emotional and behavioral functioning, and parenting stress, assessed using the Checklist for Autism Spectrum Disorder-Chinese Version (CASD-C), Pervasive Developmental Problems scale of the Child Behavior Checklist for Ages 1½-5 (CBCL 1½-5 PDP), and Parenting Stress Index-Short Form (PSI-4-SF), respectively. The primary treatment effect was evaluated using a multiple imputation-based intention-to-treat (ITT) adjusted analysis accounting for sex and baseline outcome measures. Secondary outcome analyses were interpreted with Benjamini-Hochberg false discovery rate correction for multiple comparisons. Exploratory within-group analyses and generalized estimating equation (GEE) models were used to characterize observed changes over time.
Results
Forty participants were randomized, and 38 participants completed the week 8 assessment. The ITT analysis included all randomized participants. Observed PLS total scores increased significantly within both groups. Exploratory within-group analyses also showed reductions in CASD-C social interaction issues and emotional difficulties in the Music Therapy group, and CBCL 1½-5 PDP T-scores decreased within both groups. However, the primary adjusted ITT analysis did not demonstrate statistically significant superiority of adjunctive group-based music therapy over speech therapy alone for the primary language outcome (adjusted between-group difference, -1.65; 95% confidence interval, -7.52-4.21; p = 0.569). No statistically significant adjusted between-group differences were observed for secondary outcomes. Exploratory GEE analyses indicated time-related changes in PLS total score, CASD-C sensory difficulties, and CBCL 1½-5 PDP T-score, but no significant group-by-time interactions.
Conclusion
In this exploratory RCT, group-based music therapy was feasible to integrate with speech therapy and was not associated with intervention-related adverse events. Although language performance and selected autism-related behavioral features showed improvements over time, adjunctive group-based music therapy did not demonstrate statistically significant superiority over speech therapy alone. Larger adequately powered trials are needed to evaluate its incremental benefit.
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