What are the effects of omega-3 supplementation on anthropometric measurements and thyroid function in patients with Hashimoto's disease? A randomized controlled clinical trial
Naghshi N, Mahdavi B, Bourbour F, Yari Z, Nikpayam O, Babaee Kiadehi F, Khoshdooz S, Kalbasi S, Sohrab G
Clinical nutrition ESPEN · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Shahid Beheshti University of Medical Sciences
Según 1 financiador declarado.
Publicación
- Publicado
- 2026-07-22 · Clin Nutr ESPEN · vol. 75 · pág. 103604
- Editorial
- Elsevier BV
- Citado
- 0 citas · más que el 52% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 26 trabajos
- Acceso
- De pago
- Áreas de investigación
- Fatty Acid Research and Health · Thyroid Disorders and Treatments · Systemic Lupus Erythematosus Research
- Palabras clave
- omega-3 fatty acids, Hashimoto's thyroiditis, thyroid function, thyroid peroxidase antibodies, thyroid-stimulating hormone, free thyroxine, anthropometry, autoimmune thyroid disease, dietary supplementation
- MeSH
- thyroid gland, humans, thyrotropin, thyroid hormones, triiodothyronine, thyroxine, iodide peroxidase, fatty acids, omega-3, autoantibodies, anthropometry, double-blind method, dietary supplements, adult, middle aged, female, male, hashimoto disease
9 autores
- Niayesh Naghshi🇮🇷National Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences
- Behnam Mahdavi
- Fatemeh Bourbour🇮🇷National Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences
- Zahra Yari🇮🇷National Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences
- Omid Nikpayam🇮🇷Golestan University of Medical Sciences
- Fatemeh Babaee Kiadehi🇮🇷National Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences
- Sara Khoshdooz🇮🇷Guilan University of Medical Sciences
- Saeid Kalbasi🇮🇷 · autor de correspondenciaShahid Beheshti University of Medical Sciences
- Golbon Sohrab🇮🇷 · autor de correspondenciaNational Nutrition and Food Technology Research Institute; Shahid Beheshti University; Shahid Beheshti University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background and aims
This study aimed to examine the effects of omega-3 supplementation on anthropometric measures, thyroid hormone concentrations, and anti-TPO in Hashimoto's disease patients.
Methods and materials
This double-blind randomized clinical experiment randomly split 50 Hashimoto's disease patients into two groups, including treatment and placebo, which received 2000 mg/day omega-3 or placebo for 12 weeks. Before and after the trial, anthropometric measurements and plasma thyroid hormone concentrations T3, T4, thyroid-stimulating hormone (TSH), and anti-thyroid peroxidase antibody (TPO) were measured.
Results
This research found that omega-3 supplementation in comparison with placebo significantly increased the serum level of group T4 (p = 0.032). Compared to the control group, the omega-3 group had a significant effect on the level of Anti-TPO (p = 0.040). The changes of TSH and T3 were not significantly different between intervention and control groups (p = 0.694 and p = 0.567).
Conclusion
This research found that administrating omega-3 in Hashimoto's disease enhanced thyroid function and less autoimmune activity.
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