Financiado en parte por Axanova AG
Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion: A Randomized Controlled Trial
Buehler C, Romitti R, Wellauer V, Clijsen R, Hohenauer E
International journal of environmental research and public health · 0 citas
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Cómo se estudió
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- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
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Quién lo pagó
- Financiación
- Financiado por la industria
- Empresa
- Axanova AG
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2026-07-09 · Int J Environ Res Public Health · vol. 23 · número 7 · pág. 887
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 0 citas · más que el 46% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 38 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Exercise and Physiological Responses · Sports Performance and Training · Cardiovascular and exercise physiology
- Palabras clave
- local cryotherapy, exercise-induced muscle damage, delayed onset muscle soreness, muscle fatigue recovery, creatine kinase, C-reactive protein, erythrocyte sedimentation rate, muscle thickness, vastus lateralis, post-exercise recovery
- MeSH
- muscle, skeletal, humans, creatine kinase, cryotherapy, muscle fatigue, isometric contraction, time factors, adult, female, male, cold temperature, physical exertion, young adult, myalgia, post-exercise recovery, post-exercise recovery techniques
5 autores
- Callum Buehler🇨🇭University of Applied Sciences and Arts of Southern Switzerland
- Ronja Romitti🇨🇭University of Applied Sciences and Arts of Southern Switzerland
- Vanessa Wellauer🇨🇭University of Applied Sciences and Arts of Southern Switzerland
- Ron Clijsen🇨🇭🇧🇪Bern University of Applied Sciences; Vrije Universiteit Brussel; University of Applied Sciences and Arts of Southern Switzerland; THIM van der Laan University College Physiotherapy
- Erich Hohenauer🇨🇭🇫🇷 · autor de correspondenciaUniversity of Applied Sciences and Arts of Southern Switzerland; University of Fribourg; Université de Poitiers
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Local cryotherapy is widely used to support recovery after exercise-induced muscle damage, but the optimal timing of cold application remains unclear. This study evaluated whether immediate or delayed local cooling influences recovery from exercise-induced muscle fatigue.
Methods
Forty-eight healthy adults (39 women, 9 men; age 22 ± 3 years) performed a single-leg eccentric leg-extension protocol to induce delayed-onset muscle soreness (DOMS) and were randomized to immediate cooling (ICG), delayed cooling (DCG; starting 24 h post-exercise), or control (CG) in a 1:1:1 ratio. Reusable gel packs (20 min per session) were applied to the vastus lateralis. DOMS, maximal voluntary isometric contraction (MVIC), creatine kinase (CK), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and ultrasound-derived muscle thickness (MT) were assessed at baseline and at 24, 48 and 72 h post-exercise and analyzed using linear mixed-effects models.
Results
No condition or condition-by-time interactions were detected for the primary outcomes (DOMS, MVIC). Significant linear time effects were observed for DOMS, CK and ESR; MVIC decreased acutely and gradually recovered. A contrast-specific time-by-condition interaction for CRP did not indicate a systematic recovery advantage, and MT showed only minor temporal fluctuations.
Conclusion
Neither immediate nor delayed cooling provided a meaningful recovery advantage over the control. The protocol reproducibly elicited fatigue and recovery dynamics, supporting its utility as a framework for future cryotherapy research.
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