Effects of five-element music therapy on chemotherapy patients with cancer: A systematic review and meta-analysis of randomized controlled trials
Sun T, Zhao R, Shan X, Zhu Y, Zhang Y, Zheng Y
Complementary therapies in medicine · 0 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- State Administration of Traditional Chinese Medicine of the People's Republic of China
- Gobierno
- National Administration of Traditional Chinese Medicine
Según 2 financiadores declarados.
Publicación
- Publicado
- 2026-08-04 · Complement Ther Med · vol. 101 · pág. 103411
- Editorial
- Elsevier BV
- Citado
- 0 citas · más que el 60% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 34 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Music Therapy and Health · Pain Management and Placebo Effect · Acupuncture Treatment Research Studies
- Palabras clave
- Randomized controlled trial, Music therapy, Chemotherapy, MEDLINE, Alternative medicine
- MeSH
- humans, neoplasms, antineoplastic agents, music therapy, depression, anxiety, quality of life, randomized controlled trials as topic, sleep quality
6 autores
- Tao Sun🇨🇳First Affiliated Hospital of Henan University
- Ruping Zhao🇨🇳First Affiliated Hospital of Henan University
- Xishen Shan🇨🇳First Affiliated Hospital of Henan University
- Yuanzhe Zhu🇨🇳First Affiliated Hospital of Henan University
- Yaling Zhang🇨🇳First Affiliated Hospital of Henan University
- Yuling Zheng🇨🇳 · autor de correspondenciaFirst Affiliated Hospital of Henan University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
This study aims to systematically evaluate the effects of Five-Element Music Therapy (FEMT) on emotional state, sleep quality, and quality of life in cancer patients undergoing chemotherapy.
Methods
We systematically searched 8 databases for randomized controlled trials (RCTs) comparing FEMT with standard care or control music interventions. Cochrane Risk of Bias Tool 2 (ROB2) was used to assess the quality of included RCTs. Meta-analysis was performed using Review Manager 5.4, and sensitivity analysis was conducted with Stata 18 software. GRADE system was used to assess evidence quality. Additionally, trial sequence analysis (TSA) was employed to evaluate the reliability of conclusions regarding intervention effects.
Results
A total of 20 RCTs (1588 patients) were included. Meta-analysis results showed that compared with control group, FEMT significantly reduced anxiety scores (Self-Rating Anxiety Scale (SAS): MD = -7.16, 95% CI: -9.56 to -4.67, p +% and CD4+%) and inflammatory markers (increased superoxide dismutase (SOD), decreased nitric oxide (NO)). However, the methodological quality of included studies was generally low, with most outcomes graded as low or very low certainty evidence.
Conclusion
Current evidence suggests that FEMT may effectively alleviate anxiety and depression in chemotherapy patients, improve sleep and quality of life, and exert certain physiological regulatory effects. However, due to limitations in the number, characteristics and methodological quality of studies, the generalizability of this therapy outside of China remains unclear; further validation is needed through high-quality, large-scale, international, multicenter RCTs.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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