The Portfolio diet and disease outcomes: a systematic review and meta-analysis of observational studies
Chan VWK, Gebretsadik GG, Tse MTH, Lai GZ, Leung LY, Glenn AJ, Kendall CWC, Kavanagh ME, Chiavaroli L, Jenkins DJA, Sievenpiper JL, Lo KKH
Critical reviews in food science and nutrition · 0 citas
Cómo se estudió
- Diseño
- Metaanálisis (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Hong Kong Polytechnic University
Según 1 financiador declarado.
Publicación
- Publicado
- 2026-08-12 · Crit Rev Food Sci Nutr · págs. 1–11
- Editorial
- Taylor & Francis
- Citado
- 0 citas · más que el 61% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 57 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nutritional Studies and Diet · Lipoproteins and Cardiovascular Health · Cardiovascular Health and Risk Factors
- Palabras clave
- Portfolio diet, dietary adherence, cardiovascular disease, all-cause mortality, type 2 diabetes, cancer risk, hyperlipidemia, disease outcome
12 autores
- Vicky Wai Ki Chan🇭🇰Hong Kong Polytechnic University
- Gebretsadkan Gebremedhin Gebretsadik🇭🇰🇪🇹Hong Kong Polytechnic University; Mekelle University
- Michael Tse🇭🇰Hong Kong Polytechnic University
- Gianna Zhi-Yang Lai🇭🇰Hong Kong Polytechnic University
- Leona Yuen Ling Leung🇭🇰Hong Kong Metropolitan University
- Andrea J. Glenn🇺🇸Harvard University; New York University
- Cyril W.C. Kendall🇨🇦St. Michael's Hospital; University of Toronto; University of Saskatchewan; Unity Health Toronto
- Meaghan E Kavanagh🇺🇸Harvard University
- Laura Chiavaroli🇨🇦St. Michael's Hospital; University of Toronto; Unity Health Toronto
- David J.A. Jenkins🇨🇦St. Michael's Hospital; University of Toronto; Unity Health Toronto
- John L. Sievenpiper🇨🇦St. Michael's Hospital; University of Toronto; Unity Health Toronto
- Kenneth Ka Hei Lo🇭🇰 · autor de correspondenciaHong Kong Polytechnic University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Emerging evidence suggests the Portfolio diet may confer benefits beyond managing hyperlipidemia. This systematic review and meta-analysis evaluated the association between adherence to the Portfolio diet and disease outcomes in observational studies. Four databases were searched through September 2025, and 10 studies consisting of 513,284 participants were included. Data from 4 prospective cohort studies (n = 352,396) were pooled using random-effects models for disease outcomes. Each 1-standard deviation increase in the Portfolio Diet Score (PDS) was associated with a 6% lower risk of cardiovascular disease (CVD) (RR = 0.94, 95% CI: 0.92 to 0.96) and a 10% lower risk of all-cause mortality (RR = 0.90, 95% CI: 0.86 to 0.95). Qualitative synthesis suggested that higher adherence to the Portfolio diet was associated with lower type 2 diabetes (T2D) risk and lower odds of cancer. In conclusion, higher adherence to the Portfolio diet is inversely associated with risks of CVD and mortality, while the favorable associations with T2D and cancer remain preliminary and hypothesis-generating.
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