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Effects of dietary nitrate supplementation on peak oxygen uptake following 10 days of Ramadan fasting in healthy adults

Bhimani MM, Bommarito JC, Miners NI, Khangura PK, Stapleton RK, Sharma A, Thiessen JS, Cyr NO, McCarthy DG, Dong J, Cho CE, Millar PJ

Experimental physiology · 1 cita

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación independiente
Gobierno
Natural Sciences and Engineering Research Council of Canada
Subvenciones
Natural Sciences and Engineering Research Council of Canada (2020‐04287)

Según 1 financiador declarado y la declaración de financiación del texto completo.

Publicación

Publicado
2026-08-18 · Exp Physiol · vol. 111 · número 10 · págs. 4636–4645
Editorial
Wiley
Citado
0 citas · más que el 65% de estudios similares · 0.0× el promedio de su campo
Referencias
44 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Dietary Effects on Health · Cardiovascular and exercise physiology · Muscle metabolism and nutrition
Palabras clave
nitrate supplementation, beetroot juice, Ramadan fasting, peak oxygen uptake, cardiorespiratory fitness, exercise performance, blood pressure, sleep quality, body mass
MeSH
humans, nitrates, exercise test, exercise, fasting, oxygen consumption, blood pressure, dietary supplements, islam, adult, female, male, young adult, intermittent fasting

12 autores

  • Mikail M. Bhimani🇨🇦University of Guelph
  • Julian C. Bommarito🇨🇦University of Guelph
  • Natalie I Miners🇨🇦University of Guelph
  • Pardeep K Khangura🇨🇦University of Guelph
  • Rileigh K Stapleton🇨🇦University of Guelph
  • Ashly Sharma🇨🇦University of Guelph
  • Johan S. Thiessen🇨🇦University of Guelph
  • Nicolas O. Cyr🇨🇦University of Guelph-Humber; University of Guelph
  • Devin G. McCarthy🇨🇦University of Guelph
  • Jianzhang Dong🇨🇦University of Guelph
  • Clara E. Cho🇨🇦University of Guelph
  • Philip James Millar🇨🇦University of Guelph

Resumen

El texto original del estudio, en el idioma en que se publicó.

Ramadan is a sacred religious practice observed by Muslims that involves abstaining from food and water from sunrise to sunset for 1 month. Prior work has reported that peak oxygen uptake ( V̇O2peak ) can decline during Ramadan in parallel with reduced physical activity. We investigated whether dietary nitrate supplementation could attenuate the decrease in V̇O2peak during 10 days of Ramadan fasting. In a randomized design, 21 healthy participants (13 females) were assigned to ingest 70 mL of beetroot juice (∼6.45 mmol nitrate; n = 10), twice a day for 10 days consecutively, or a non-supplement control (n = 11). The V̇O2peak was assessed by indirect calorimetry during a maximal cycle ergometer ramp test. After 10 days of Ramadan fasting, the change in body mass was not different between groups [change (∆), -0.91 ± 1.3 vs. -0.27 ± 1.2 kg (control vs. nitrate), P = 0.25], nor were the changes in resting systolic (P = 0.21) or diastolic (P = 0.53) blood pressure or urine specific gravity (P = 0.17). Subjective sleep quality declined over time in both groups (P -1, P -1 min-1, P = 0.02) and peak power output (∆, -12 ± 16 vs. ∆+2 ± 10 W, P = 0.04). Dietary nitrate supplementation might represent a practical nutritional strategy to preserve aerobic capacity during Ramadan fasting.

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