Football-Specific Performance and Cognitive Fatigue Resistance Following Supplementation with Two Phosphatidylserine Doses Combined with Taurine and Caffeine in Professional Male Football Players: A Randomized, Triple-Masked, Placebo-Controlled Trial
Mizera K, Mazurek D, Martínez-Rodríguez A, Kęska A
Nutrients · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2026-08-07 · Nutrients · vol. 18 · número 16 · pág. 2588
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 0 citas · más que el 61% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 42 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Sports Performance and Training · Exercise and Physiological Responses · Muscle metabolism and nutrition
- Palabras clave
- phosphatidylserine, taurine, caffeine, mental fatigue, psychomotor performance, reaction time, Stroop task, sprint performance, locomotor performance, football players, professional athletes, dietary supplementation, match performance, GPS tracking, dose comparison, fatigue recovery
- MeSH
- humans, taurine, caffeine, phosphatidylserines, double-blind method, mental fatigue, cognition, psychomotor performance, reaction time, soccer, dietary supplements, adult, male, athletic performance, young adult, athletes
4 autores
- Krzysztof Maciej Mizera🇵🇱VIZJA University
- Dominik Mazurek🇵🇱VIZJA University
- Alejandro Martínez‐Rodríguez🇪🇸University of Alicante
- Anna Kęska🇵🇱Józef Piłsudski University of Physical Education in Warsaw
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background/objectives
Cognitive fatigue and impaired psychomotor function may contribute to reductions in football-specific performance during prolonged match-like activity. This study evaluated cognitive, psychomotor, sprint, and football-specific locomotor responses to multi-ingredient protocols containing taurine, caffeine, and either 300 or 600 mg·day-1 of phosphatidylserine in professional male football players.
Methods
In this randomized, triple-masked, placebo-controlled, parallel-group trial, 97 professional male football players were allocated to placebo (PLA, n = 24), taurine plus caffeine (TC, n = 24), taurine plus caffeine plus phosphatidylserine 300 mg·day-1 (TCP-300, n = 24), or taurine plus caffeine plus phosphatidylserine 600 mg·day-1 (TCP-600, n = 25) for 14 days. Taurine and caffeine doses were 1500 mg·day-1 and 200 mg·day-1, respectively. Outcomes included 30 m sprint performance, visual and auditory reaction time, Stroop-task performance, perceived mental fatigue, GPS-derived locomotor variables, and post-intervention first-to-second-half performance-loss indices during a standardized football-specific exercise protocol.
Results
The baseline-adjusted ANCOVA demonstrated a significant treatment-group effect on post-intervention 30 m sprint time. After Holm-Bonferroni correction, significant treatment-related effects remained for Stroop reaction time, visual reaction time, and perceived mental fatigue. No statistically significant treatment-related effect was observed for auditory reaction time (unadjusted p = 0.074; Holm-adjusted p = 0.096). During the post-intervention standardized football-specific protocol, baseline-adjusted GPS-derived locomotor outcomes differed significantly between groups. First-to-second-half performance-loss indices also differed between groups, with the smallest post-intervention losses generally observed in TCP-600. Because comparable decline indices were unavailable at baseline, these findings do not represent intervention-related changes in fatigue resistance.
Conclusions
Under the present 14-day experimental conditions, the multi-ingredient protocols containing taurine, caffeine, and phosphatidylserine were associated with more favorable selected cognitive and psychomotor outcomes, 30 m sprint performance, and baseline-adjusted GPS-derived locomotor outcomes than placebo. The groups also differed in post-intervention first-to-second-half performance loss during the standardized football-specific protocol. Because corresponding decline indices were not assessed at baseline, these findings do not demonstrate an intervention-related improvement in fatigue resistance. Numerically more favorable values were observed for several outcomes in TCP-600; however, differences between TCP-300 and TCP-600 were modest and not consistently statistically significant, and the study was not specifically powered to establish a dose-response relationship. Because phosphatidylserine was not tested independently, these findings should be interpreted as responses to the combined multi-ingredient supplementation protocols rather than as effects of phosphatidylserine alone.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.