Comparison of Traditional Chinese Exercise and Equipment-Based Exercise on Glycaemic Control and Vitamin D Levels in Middle-Aged and Elderly Patients With Prediabetes: A Randomised Controlled Trial
Lingzhi X, Chunhua Z, Wu L, Jiejin D, Yimin Y
Endocrinology, diabetes & metabolism · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2026-09-01 · Endocrinol Diabetes Metab · vol. 9 · número 5 · pág. e70326
- Editorial
- Bioscientifica
- Citado
- 0 citas · más que el 71% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 10 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Physical Activity and Health · Diabetes, Cardiovascular Risks, and Lipoproteins · Diabetes Treatment and Management
- Palabras clave
- prediabetes, traditional Chinese exercise, vitamin D, 25-hydroxyvitamin D, glycemic control, HbA1c, fasting blood glucose, type 2 diabetes prevention, middle-aged and older adults, lipid profile, body composition, exercise intervention, physical inactivity, vitamin D supplementation, dietary fat
- MeSH
- humans, prediabetic state, calcifediol, blood glucose, vitamin d, exercise, exercise therapy, aged, middle aged, female, male, glycemic control, glycated hemoglobin
5 autores
- Xu Lingzhi
- Zhou Chunhua
- Liu Wu
- Ding Jiejin
- Yuan Yimin · autor de correspondencia
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Prediabetes is a critical window for preventing progression to type 2 diabetes mellitus (T2DM). Both vitamin D deficiency and physical inactivity are associated with impaired glucose metabolism. This study compared the effects of Traditional Chinese Exercise (TCE) and Kuanle Equipment Exercise (KEE) on glycaemic measures, lipid profiles, body composition and serum 25-hydroxyvitamin D3 [25(OH)D3] in middle-aged and elderly adults with prediabetes.
Methods
We conducted a 12-week, single-centre, randomised controlled trial involving 62 participants with prediabetes (mean age 55.2 ± 8.4 years; 88.7% female). Participants were randomly assigned to control (usual care, n = 21), TCE (n = 20), or KEE (n = 21). Primary outcomes included fasting plasma glucose (FPG), 2-h OGTT glucose, glycated haemoglobin (HbA1c) and serum 25(OH)D3. Secondary outcomes comprised triglycerides, total cholesterol, LDL-C, HDL-C and body composition.
Results
At baseline, mean serum 25(OH)D3 was 21.53 ± 3.90 nmol/L. At 12 weeks, both TCE and KEE improved FPG, 2-h OGTT glucose, HbA1c and 25(OH)D3 versus control (all p ≤ 0.001). Relative changes in FPG were -9.4% (TCE) and -15.2% (KEE) versus -1.5% (control); corresponding changes were -14.6% and -21.2% for 2-h OGTT glucose, -6.7% and -12.9% for HbA1c, and +60.6% and +81.9% for 25(OH)D3. Direct TCE-KEE comparisons were not significant (all p > 0.05). In an exploratory analysis, change in 25(OH)D3 was inversely associated with change in 2-h OGTT glucose (partial r = -0.358, p = 0.006), but not with FPG, HbA1c, or triglycerides.
Conclusions
Both TCE and KEE improved glycaemic outcomes and increased serum 25(OH)D3 compared with usual care in middle-aged and elderly adults with prediabetes. Although KEE produced numerically larger estimates, direct between-group comparisons were not significant, and the superiority of KEE over TCE was not established. These vitamin D findings require confirmation in trials that quantify sunlight exposure and dietary vitamin D intake.
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