Music therapy in artificial insemination by husband: Effects on psychological distress and clinical pregnancy rate
Jin X, Hu R, Zhu X, Chen X
Medicine · 0 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Department of Education of Zhejiang Province
Según 1 financiador declarado.
Publicación
- Publicado
- 2026-09-11 · Medicine (Baltimore) · vol. 105 · número 37 · pág. e50655
- Editorial
- Wolters Kluwer
- Citado
- 0 citas · más que el 74% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 18 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Music Therapy and Health · Reproductive Health and Technologies · Maternal Mental Health During Pregnancy and Postpartum
- Palabras clave
- music therapy, artificial insemination by husband, infertility, psychological distress, anxiety, depression, stress, clinical pregnancy, music listening
- MeSH
- humans, music therapy, insemination, artificial, pregnancy rate, depression, stress, psychological, anxiety, spouses, pregnancy, adult, female, psychological distress
4 autores
- Xianwen Jin
- Rubing Hu
- Xiaocha Zhu
- Xuewei Chen
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Infertility treatment can be psychologically burdensome. Evidence on music listening during artificial insemination by husband (AIH) remains limited. We evaluated whether a standardized periprocedural music intervention reduced psychological distress and explored its association with clinical pregnancy.
Methods
In this single-center, open-label randomized trial, 254 women undergoing AIH were allocated 1:1 to routine care or routine care plus two 30-minute music-listening sessions, immediately before and after AIH. The prespecified primary outcome was the continuous 21-item Depression Anxiety Stress Scales (DASS-21) score at follow-up; clinical pregnancy was secondary. DASS-21 was completed at baseline and at day 35 after AIH. Clinical pregnancy was assessed by ultrasonography at days 30 to 35.
Results
Continuous DASS-21 anxiety, depression, and stress scores did not differ between groups after adjustment for baseline scores (all P ≥ .868). Absolute postintervention differences were 0.01 point or less for anxiety and depression and 0.08 point for stress, indicating neither statistical nor clinically meaningful improvement. Clinical pregnancy occurred in 34/127 participants (26.77%) in the intervention group and 14/127 (11.02%) in the control group (exploratory secondary outcome; P = .001).
Conclusion
The intervention did not improve the primary psychological outcome. The higher clinical pregnancy rate is hypothesis-generating because the trial was not powered for pregnancy, the proposed psychological mechanism was not demonstrated, and nonspecific attention and other unmeasured factors cannot be excluded. Replication using an attention-matched control, immediate state-anxiety and physiological measures, participant-preference assessment, and live-birth follow-up is required.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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