Financiado en parte por Kellogg's, Kellogg's (United States)
Whole Grain Oats and Barley Products Modify Lipoproteins and Cardiometabolic Risk Markers in Adults: A 6-Week, Double-Blind, Parallel Design, Randomized Controlled Feeding Trial
Stote KS, Baer DJ, Henderson T, Solano-Aguilar GI, Terekhov A, Hamaker BR, Novotny JA
Nutrients · 0 citas
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Cómo se estudió
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- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
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- Comida provista por los investigadores
Quién lo pagó
- Financiación
- Financiado por la industria
- Gobierno
- U.S. Department of Agriculture
- Empresa
- Kellogg's
- Empresa
- Kellogg's (United States)
- Subvenciones
- Kellogg's (1235-51530-009-17T); U.S. Department of Agriculture (1235-51530-009-00D)
Según 3 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2026-09-02 · Nutrients · vol. 18 · número 17 · pág. 2873
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 0 citas · más que el 67% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 43 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Food composition and properties · Nutritional Studies and Diet · Lipoproteins and Cardiovascular Health
- Palabras clave
- whole grain oats, whole grain barley, β-glucan, cardiovascular risk, LDL cholesterol, LDL particle size, lipoproteins, VLDL, chylomicrons, blood pressure, VCAM-1, inflammation, dietary intervention
- MeSH
- humans, hordeum, cardiovascular diseases, beta-glucans, lipoproteins, double-blind method, adult, middle aged, female, male, cholesterol, ldl, biomarkers, avena, whole grains, cardiometabolic risk factors
7 autores
- Kim S. Stote🇺🇸Agricultural Research Service; Beltsville Human Nutrition Research Center; Empire State University
- David J. Baer🇺🇸Agricultural Research Service; Beltsville Human Nutrition Research Center
- Theresa Henderson🇺🇸Agricultural Research Service; Beltsville Human Nutrition Research Center
- Gloria Isabel Solano-Aguilar🇺🇸Agricultural Research Service; Beltsville Human Nutrition Research Center
- Anton Terekhov🇺🇸Purdue University West Lafayette
- Bruce R. Hamaker🇺🇸Purdue University West Lafayette
- Janet A. Novotny🇺🇸 · autor de correspondenciaAgricultural Research Service; Beltsville Human Nutrition Research Center
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background/Objectives: Oats and barley are β-glucan-rich grains that may reduce risk factors for cardiovascular disease in adults. This study was conducted to evaluate the effects of products made with either whole grain barley or whole grain oats on CVD risk factors in adults. Methods: A 6-week, double-blind, parallel-design, randomized, controlled feeding trial was conducted with 68 adults. Subjects were randomly assigned to either: (1) a control diet containing 0.8 daily servings of whole grain per 2000 kcal, (2) a diet containing 4 daily servings of whole grain oats per 2000 kcal, or (3) a diet containing 4 daily servings of whole grain barley per 2000 kcal. Markers of cardiovascular disease risk were assessed before and after treatment. Results: LDL cholesterol concentrations show a trend of statistical significance across diets (p = 0.0638), with a lowering of 8.9 mg/dL (barley) and 11.2 mg/dL (oats) compared to the control. Both whole grain diets significantly lowered total VLDL and chylomicron particles (p = 0.0272). The oat diet significantly lowered total LDL particles (p = 0.0014), small LDL particles (p = 0.0008), medium-small LDL particles (p = 0.0008), and very small LDL particles (p = 0.0009) and increased LDL particle size (p = 0.0451). The barley diet significantly lowered diastolic blood pressure (p = 0.0388) and vascular cell adhesion molecule concentrations (p = 0.0320). Conclusions: Diets containing products made from whole grain oats may improve blood lipid profiles, while diets containing products made from whole grain barley may provide additional benefits for blood pressure and inflammation.
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