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Ensayo controlado aleatorizado1994

Caffeine effects on learning, performance, and anxiety in normal school-age children

Bernstein GA, Carroll ME, Crosby RD, Perwien AR, Go FS, Benowitz NL

Journal of the American Academy of Child and Adolescent Psychiatry · 48 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Institute on Drug Abuse
Gobierno
NIDA NIH HHS
Subvenciones
National Institute on Drug Abuse (NIDA R37 DA03240); National Institute on Drug Abuse (NIDA DAO1696); National Institute on Drug Abuse (P01-DA-08131)

Según 2 financiadores declarados.

Publicación

Publicado
1994-03-01 · J Am Acad Child Adolesc Psychiatry · vol. 33 · número 3 · págs. 407–415
Editorial
Elsevier BV
Citado
107 citas · más que el 72% de estudios similares · 0.9× el promedio de su campo
Referencias
42 trabajos
Acceso
De pago
Áreas de investigación
Coffee research and impacts · Attention Deficit Hyperactivity Disorder · Neuroethics, Human Enhancement, Biomedical Innovations
Palabras clave
caffeine, children, attention, manual dexterity, short-term memory, processing speed, anxiety, cognitive performance, prepubertal children, caffeine dose-response
MeSH
saliva, humans, caffeine, anxiety, learning, task performance and analysis, psychometrics, dose-response relationship, drug, child

6 autores

  • Gail A. Bernstein🇺🇸University of Minnesota
  • Marilyn E. Carroll🇺🇸 · autor de correspondenciaSan Francisco General Hospital; University of Minnesota
  • Ross D. Crosby🇺🇸San Francisco General Hospital; University of Minnesota
  • Amy R. Perwien🇺🇸San Francisco General Hospital; University of Minnesota
  • FRANCES S. GO🇺🇸San Francisco General Hospital; University of Minnesota
  • Neal L. Benowitz🇺🇸San Francisco General Hospital; University of Minnesota

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objective

The purpose of this investigation was to study the acute effects of caffeine on learning, performance, and anxiety in normal prepubertal children.

Method

Twenty-one children were evaluated in a double-blind, placebo-controlled crossover design. Subjects were studied during four sessions, 1 week apart, under the following conditions: baseline, placebo, 2.5 mg/kg caffeine, and 5.0 mg/kg caffeine. Subjects were randomized to order of placebo and the two dosages of caffeine. Dependent measures included tests of attention, manual dexterity, short-term memory, and processing speed. Anxiety rating scales were also administered. Saliva samples were analyzed for caffeine levels.

Results

Caffeine improved performance on two of four measures of the Test of Variables of Attention and on a test of manual dexterity in the dominant hand. There was a trend toward increased current level of self-reported anxiety after caffeine on a visual analogue measure of anxiety. Children reported feeling significantly less "sluggish" after caffeine ingestion than after placebo ingestion.

Conclusions

In a small sample size, there was indication that caffeine enhanced performance on a test of attention and on a motor task. Children also reported feeling less "sluggish" but somewhat more anxious. Because caffeine is so widely available and frequently consumed by children, these results are important and need replication.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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