The effect of docosahexaenoic acid on aggression in young adults. A placebo-controlled double-blind study
Hamazaki T, Sawazaki S, Itomura M, Asaoka E, Nagao Y, Nishimura N, Yazawa K, Kuwamori T, Kobayashi M
The Journal of clinical investigation · 136 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 1996-02-15 · J Clin Invest · vol. 97 · número 4 · págs. 1129–1133
- Editorial
- American Society for Clinical Investigation
- Citado
- 275 citas · más que el 97% de estudios similares · 6.2× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 20 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Fatty Acid Research and Health · Edible Oils Quality and Analysis · Nutritional Studies and Diet
- Palabras clave
- docosahexaenoic acid, omega-3 fatty acids, fish oil supplementation, aggression, psychological stress, young adults, P-F study, Stroop task, dementia detection, coronary heart disease prevention
- MeSH
- humans, dementia, dietary fats, docosahexaenoic acids, fatty acids, nonesterified, double-blind method, aggression, adult, female, male
9 autores
- Tomohito Hamazaki🇯🇵University of Toyama
- Shigeki Sawazaki🇯🇵University of Toyama
- Miho Itomura🇯🇵University of Toyama
- Etsuko Asaoka🇯🇵University of Toyama
- Yoko Nagao🇯🇵Yokkaichi University; Yokkaichi University Junior College
- N Nishimura🇯🇵Yokkaichi University; Yokkaichi University Junior College
- Kazunaga Yazawa🇯🇵Sagami Chemical Research Institute; University of Toyama
- Toyomi Kuwamori🇯🇵Sagami Chemical Research Institute
- Makoto Kobayashi🇯🇵University of Toyama
Resumen
El texto original del estudio, en el idioma en que se publicó.
41 students took either docosahexaenoic acid (DHA)-rich oil capsules containing 1.5-1.8 grams DHA/day (17 females and 5 males) or control oil capsules containing 97% soybean oil plus 3% fish oil (12 females and 7 males) for 3 mo in a double-blind fashion. They took a psychological test (P-F Study) and Stroop and dementia-detecting tests at the start and end of the study. The present study started at the end of summer vacation and ended in the middle of mental stress such as final exams. In the control group extraggression (aggression against others) in P-F Study was significantly increased at the end of the study as compared with that measured at the start (delta = +8.9%, P = 0.0022), whereas it was not significantly changed in the DHA group (delta = -1.0%). The 95% CI of differences between the DHA and control groups were -16.8 to -3.0%. DHA supplementation did not affect the Stroop and dementia-detecting tests. Thus, DHA intake prevented extraggression from increasing at times of mental stress. This finding might help understand how fish oils prevent disease like coronary heart disease.
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