A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until two months
Carlson SE, Werkman SH
Lipids · 160 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Institutes of Health
- Gobierno
- National Eye Institute
- Gobierno
- National Institute of Child Health and Human Development
- Gobierno
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Gobierno
- NEI NIH HHS
- Gobierno
- NICHD NIH HHS
- Subvenciones
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01 HD31329); National Eye Institute (R01 EY08770)
Según 6 financiadores declarados.
Publicación
- Publicado
- 1996-01-01 · Lipids · vol. 31 · número 1Part1 · págs. 85–90
- Editorial
- Wiley
- Citado
- 322 citas · más que el 100% de estudios similares · 25.6× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 43 trabajos
- Acceso
- De pago
- Áreas de investigación
- Fatty Acid Research and Health · Infant Nutrition and Health · Infant Development and Preterm Care
- Palabras clave
- docosahexaenoic acid, preterm infants, infant formula supplementation, visual attention, novelty preference, visual recognition memory, omega-3 fatty acids, linolenic acid, information processing, marine oils
- MeSH
- humans, docosahexaenoic acids, double-blind method, visual perception, infant, infant, newborn, infant, premature, female, male
2 autores
- Susan E. Carlson🇺🇸University of Tennessee Health Science Center
- Susan H. Werkman🇺🇸University of Tennessee Health Science Center
Resumen
El texto original del estudio, en el idioma en que se publicó.
This was a randomized, double-blind trial to determine if a nutrient-enriched (preterm) formula supplemented with 0.2% docosahexaenoic acid (DHA, 22:6n-3) from a low eicosapentaenoic acid (0.06%) source of marine oil would enhance visual novelty preference and attention of preterm infants. Both the standard and experimental formulas contained 3% of total fatty acids as linolenic acid (18:3n-3) and were fed from approximately three days of age to two months past term. After two months, both diet groups were fed a commercially-available term formula with linolenic acid as the only source of n-3 fatty acid. At 12 mo visual recognition memory (novelty preference) and visual attention (number and duration of discrete looks) were determined with the Fagan Test of Infant Intelligence. The DHA-supplemented group compared with the control group had more and shorter duration looks in comparisons of familiar and novel stimuli, confirming earlier evidence that DHA can increase information processing speed of preterm infants who otherwise are receiving good intakes of linolenic acid. Because supplementation was stopped at two months and the effects seen at 12 mon, this study demonstrates for the first time that a relatively short period of DHA supplementation can produce significant effects on later visual attention.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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