Effect of creatine on aerobic and anaerobic metabolism in skeletal muscle in swimmers
Thompson CH, Kemp GJ, Sanderson AL, Dixon RM, Styles P, Taylor DJ, Radda GK
British journal of sports medicine · 49 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 1996-09-01 · Br J Sports Med · vol. 30 · número 3 · págs. 222–225
- Editorial
- BMJ
- Citado
- 100 citas · más que el 85% de estudios similares · 1.9× el promedio de su campo
- Referencias
- 21 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Cardiovascular and exercise physiology
- Palabras clave
- creatine supplementation, skeletal muscle metabolism, aerobic metabolism, anaerobic metabolism, triceps surae, plantar flexion exercise, endurance exercise, swimmers, post-exercise recovery, 31P NMR, near-infrared spectroscopy
- MeSH
- muscle, skeletal, humans, phosphorus isotopes, choline, creatine, placebos, spectroscopy, near-infrared, magnetic resonance spectroscopy, administration, oral, aerobiosis, anaerobiosis, oxygen consumption, swimming, rest, female, physical exertion
7 autores
- Courtney Thompson🇬🇧John Radcliffe Hospital
- Graham John Kemp🇬🇧John Radcliffe Hospital
- A. L. Sanderson🇬🇧John Radcliffe Hospital
- Ruth M Dixon🇬🇧John Radcliffe Hospital
- P Styles🇬🇧John Radcliffe Hospital
- D.J. Taylor🇬🇧John Radcliffe Hospital
- George K. Radda🇬🇧John Radcliffe Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
To examine the effect of a relatively low dose of creatine on skeletal muscle metabolism and oxygen supply in a group of training athletes.
Methods
31P magnetic resonance and near-infrared spectroscopy were used to study calf muscle metabolism in a group of 10 female members of a university swimming team. Studies were performed before and after a six week period of training during which they took either 2 g creatine daily or placebo. Calf muscle metabolism and creatine/choline ratios were studied in resting muscle, during plantar flexion exercise (10-15 min), and during recovery from exercise.
Results
There was no effect of creatine on metabolite ratios at rest or on metabolism during exercise and recovery from exercise. Muscle oxygen supply and exercise performance were not improved by creatine if compared to placebo treated subjects.
Conclusions
Oral creatine supplementation at 2 g daily has no effect on muscle creatine concentration, muscle oxygen supply or muscle aerobic or anaerobic metabolism during endurance exercise.
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