Olive oil and human cancer: an assessment of the evidence
Lipworth L, Martínez ME, Angell J, Hsieh CC, Trichopoulos D
Preventive medicine · 82 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Cancer Institute
- Gobierno
- NCI NIH HHS
- Subvenciones
- National Cancer Institute (T32CA09001-19A2)
Según 2 financiadores declarados.
Publicación
- Publicado
- 1997-03-01 · Prev Med · vol. 26 · número 2 · págs. 181–190
- Editorial
- Elsevier BV
- Citado
- 157 citas · más que el 98% de estudios similares · 10.1× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 82 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nutritional Studies and Diet · Edible Oils Quality and Analysis · Nuts composition and effects
- Palabras clave
- olive oil, cancer risk, monounsaturated fatty acids, breast cancer, protective effect, Mediterranean diet, food frequency questionnaire, case-control study
- MeSH
- animals, humans, rats, neoplasms, disease models, animal, dietary fats, unsaturated, plant oils, confidence intervals, odds ratio, case-control studies, research design, mediterranean region, female, male, olive oil
5 autores
- Loren Lipworth🇺🇸Harvard University
- Marı́a Elena Martı́nez🇺🇸Harvard University
- Jennifer E. Angell🇺🇸Harvard University
- Chung‐Cheng Hsieh🇺🇸Harvard University; University of Massachusetts Chan Medical School
- Dimitrios Trichopoulos🇺🇸Harvard University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
We have attempted to summarize the evidence concerning the association of olive oil intake with cancer risk in humans.
Methods
We reviewed all the studies that met the following criteria: (1) they have directly examined olive oil in the context of an extensive food frequency questionnaire or have evaluated the role of monounsaturated fat in populations of Mediterranean countries where a large fraction of monounsaturated fat originates from olive oil and (2) they have analyzed the data with explicit or implicit control for energy intake to accommodate the likely confounding influence of caloric consumption and to account to a certain extent for differential completeness of reporting between cases and controls. Ecologic studies were also considered and relevant experimental data were invoked.
Results
With respect to breast cancer, there is converging evidence for a protective effect, although the data are not definitive. For other cancer types, the overall epidemiologic evidence, although promising, is quantitatively limited and qualitatively suboptimal.
Conclusions
The issue is of major public health importance and deserves additional study.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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